Predictors of 10-year mortality in a population of community-dwelling Brazilian elderly: the Bambuí cohort study of aging

Predictors of 10-year mortality in a population of community-dwelling Brazilian elderly: the Bambuí cohort study of aging
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DOI:
10.1590/s0102-311x2011001500006
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发表时间:
2011-01-01
期刊:
Cadernos de Saúde Pública
影响因子:
--
通讯作者:
Uchôa, Elizabeth
Uchôa, Elizabeth
中科院分区:
其他
文献类型:
--
作者:
Lima-Costa, Maria Fernanda;Peixoto, Sergio Viana;Uchôa, Elizabeth

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我们使用来自班布伊老龄化队列研究的1,399名60岁及以上参与者的数据,研究社会经济弱势人群死亡率的预测因素。从1997年到2007年,599名参与者死亡,6.2%失访,导致12,415人年(pyrs)的观察。死亡率为48.3/1000 pyrs。年龄(校正风险比[HR] = 1.40),男性(HR = 1.80),从未结婚(HR = 1.78)或寡妇(HR = 1.26),自评健康状况较差(HR = 1.31),无法进行四项或更多日常生活活动(HR = 3.29),心血管危险因素数量(2例HR = 1.51,3例或以上HR = 1.91),克氏锥虫感染(FIR = 1.27)和药物数量(HR = 1.06)均与死亡率显著(p < 0.05)且独立相关。简易精神状态检查评分显示保护作用(HR = 0.96)。除了T.其他死亡率预测因子与较富裕的老年人群中发现的预测因子高度一致。
We used data on 1,399 participants aged 60 and over from the Bambui Cohort Study of Aging to examine predictors of mortality in a socioeconomically disadvantaged population. From 1997 to 2007, 599 participants died and 6.2% were lost to follow-up, leading to 12,415 person-years (pyrs) of observation. The death rate was 48.3 per 1,000 pyrs. Age (adjusted hazard ratio [HR] = 1.40), male gender (HR = 1.80), never married (HR = 1.78) or a widow (HR = 1.26), poor self-rated health (HR = 1.31), inability to perform four or more activities of daily living (HR = 3.29), number of cardiovascular risk factors (HR = 1.51 for two and HR = 1.91 for three or more), Trypanosoma cruzi infection (FIR = 1.27), and number of medications (HR = 1.06) were each significantly (p < 0.05) and independently associated with mortality The Mini-Mental State Examination score showed a protective effect (HR = 0.96). Except T. cruzi infection, other predictors of mortality were highly consistent with those found in more affluent elderly populations.