Rhodium-Catalyzed Three-Component Reaction between Silylacetylene and Two Ketenes Leading to 1,3-Enynes Bearing a Carboxylic Ester Group via Double Insertion of Ketenes
Rhodium-Catalyzed Three-Component Reaction between Silylacetylene and Two Ketenes Leading to 1,3-Enynes Bearing a Carboxylic Ester Group via Double Insertion of Ketenes
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铑催化甲硅烷基乙炔和两个乙烯酮之间的三组分反应，通过乙烯酮的双重插入生成带有羧酸酯基团的 1,3-烯炔
DOI：
10.1021/ol301897h
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发表时间：
2012
期刊：
影响因子：
5.2
通讯作者：
Kenichi Ogata
中科院分区：
文献类型：
--
作者：
N. Sano;W. Tomita;S. Hara;C. -H. Min;J. -S. Lee;K. Oyaizu;H. Nishide;Claudio Toncelli;Naoki Sano;佐野直樹;Naoki Sano;Kenichi Ogata
使用阳离子铑络合物催化剂实现末端甲硅烷基乙炔和两个烯酮分子之间的第一交叉反应，通过烯酮的双插入导致带有羧酸酯基团的1，3-烯炔。该反应适用于各种对称和不对称烯酮的合成，具有良好的立体选择性。
The first cross-reaction between a terminal silylacetylene and two ketene molecules leading to 1,3-enynes bearing a carboxylic ester group via double insertion of ketenes is achieved using a cationic rhodium complex catalyst. This reaction is applicable for various symmetrical and unsymmetrical ketenes with good stereoselectivities.