Synthesizing cellular LOGIC
Synthesizing cellular LOGIC
复制标题
综合细胞逻辑
DOI:
10.1038/s41589-023-01280-y
复制
发表时间:
2023
影响因子:
14.8
通讯作者:
Wilson, Corey J.
中科院分区:
文献类型:
--
作者:
Huang, Brian D.;De Pereda, Ana S.;Wilson, Corey J.
Engineering synthetic tools that facilitate decision-making in mammalian cells could enable myriad biomedical applications. Researchers have now developed a new system of inducer-controlled transcription factors to facilitate synthetic decision-making (LOGIC) in human cells based on modular protein-fusion cascades.