Phycocyanin: A Potential Drug for Cancer Treatment.

Phycocyanin: A Potential Drug for Cancer Treatment.
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藻蓝蛋白:一种潜在的癌症治疗药物

DOI:
10.7150/jca.21058
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发表时间:
2017
期刊:
影响因子:
3.9
通讯作者:
Li B
Li B
中科院分区:
医学3区
文献类型:
--
作者:
Jiang L;Wang Y;Yin Q;Liu G;Liu H;Huang Y;Li B

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从海洋生物中分离得到的藻蓝蛋白具有高效、低毒的特点,可作为功能性食品加以利用。有报道称藻蓝蛋白具有抗氧化功能、抗炎活性、抗癌功能、增强免疫功能、保护肝肾的药理作用。因此,藻蓝蛋白作为一种潜在的药物具有重要的开发利用价值,藻蓝蛋白已成为药物研究领域的新热点。到目前为止,越来越多的研究表明藻蓝蛋白具有抗癌作用,可以阻断癌细胞的增殖,杀死癌细胞。藻蓝蛋白通过阻断肿瘤细胞的细胞周期,诱导肿瘤细胞凋亡和自噬,发挥抗癌作用,是一种很有前景的抗癌药物。本文综述了藻蓝蛋白的治疗应用,重点介绍了藻蓝蛋白作为一种很有前景的抗癌药物的最新研究进展。
Phycocyanin isolated from marine organisms has the characteristics of high efficiency and low toxicity, and it can be used as a functional food. It has been reported that phycocyanin has anti-oxidative function, anti-inflammatory activity, anti-cancer function, immune enhancement function, liver and kidney protection pharmacological effects. Thus, phycocyanin has an important development and utilization as a potential drug, and phycocyanin has become a new hot spot in the field of drug research. So far, there are more and more studies have shown that phycocyanin has the anti-cancer effect, which can block the proliferation of cancer cells and kill cancer cells. Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, thereby phycocyanin can serve as a promising anti-cancer agent. This review discusses the therapeutic use of phycocyanin and focuses on the latest advances of phycocyanin as a promising anti-cancer drug.
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