MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis.
MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis.
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DOI：
10.17912/micropub.biology.000427
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发表时间：
2021
影响因子：
--
通讯作者：
Shakes DC
中科院分区：
文献类型：
--
作者：
Morrison KN;Uyehara CM;Ragle JM;Ward JD;Shakes DC
直到最近，秀丽隐杆线虫精母细胞内纤维体（FB）的唯一经证实的组分是主要精子蛋白（MSP），一种线虫特异性细胞骨架元件。早期的研究猪蛔虫寄生虫已确定辅助蛋白，促进MSP聚合和解聚内的伪足爬行精子。在这项研究中，我们表明，C。蛔虫辅助蛋白MFP1和MFP2的同源物与MSP共定位于线虫的两个伪足中。elegans精子和C.精母细胞
Until recently, the only verified component of Fibrous Bodies (FBs) within Caenorhabditis elegans spermatocytes was the Major Sperm Protein (MSP), a nematode-specific cytoskeletal element. Earlier studies in the pig parasite Ascaris suum had identified accessory proteins that facilitate MSP polymerization and depolymerization within the pseudopod of crawling spermatozoa. In this study, we show that C. elegans homologs of the two Ascaris accessory proteins MFP1 and MFP2 co-localize with MSP in both the pseudopods of C. elegans sperm and the FBs of C. elegans spermatocytes.