Experiences of intra-articular administration of radioactive gold.
Experiences of intra-articular administration of radioactive gold.
复制标题
放射性金关节内注射的经验。
DOI：
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发表时间：
1967
期刊：
影响因子：
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通讯作者：
T. Heiskanen
中科院分区：
文献类型：
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作者：
M. Virkkunen;F. Krusius;T. Heiskanen
90例患者共156次关节内应用剂量为1 - 10mc的放射性金混悬液。通过扫描表明，在大多数情况下，放射性扩散超出了治疗关节，扩散程度有很大的个体差异。19例中有18例计算的肝脏辐射剂量不显著；只有一个例外的情况下，其大小与腹部x线检查大致相同。27例中有5例局部淋巴结放射剂量较大，1例甚至出现淋巴结放射损伤征象。主要基于85例慢性膝关节积液的临床观察表明，在大多数病例中，关节内应用放射性金的效果是有利的，至少与用四氧化锇产生的效果相似。该系列对其他关节的影响太小，无法保证临床结论。
SummaryIntra-articular applications of radio-gold suspensions in doses of 1—10 mc were given a total of 156 times to 90 patients. It was shown by means of scanning that in the majority of cases radioactivity spread beyond the joint treated and that there were great individual differences in the degree of diffusion. The calculated radiation dose to the liver was insignificant in 18 cases out of 19; only in one exceptional case was it of about the same magnitude as in thorough abdominal roentgen examinations. The radiation dose to the regional lymph nodes was considerable in 5 out of 27 cases, and 1 case even displayed signs of radiation injury in the node. Clinical observations, based mainly on 85 cases of chronic knee hydrops, showed the effect of intra-articular application of radio-gold to be favourable in the majority of the cases and at least similar to that produced by means of osmium tetroxide. The series was too small in regard to the other joints to warrant clinical conclusions.