The role of the frontal cortex in task preparation

The role of the frontal cortex in task preparation
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DOI:
10.1093/cercor/12.9.908
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发表时间:
2002-09-01
期刊:
影响因子:
3.7
通讯作者:
von Cramon, DY
von Cramon, DY
中科院分区:
医学2区
文献类型:
--
作者:
Brass, M;von Cramon, DY

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准备任务的能力对于自主控制我们的行为至关重要。它使我们能够灵活迅速地对变化的环境作出反应。在事件相关的功能磁共振成像研究中,我们用任务提示范式研究了任务准备。在这个范例中,我们将任务提示和目标同时呈现的试验与只呈现任务提示的试验混合在一起。对这些仅线索试验的分析使我们能够将任务准备相关的控制与执行相关的控制过程分离开来。通过这一范式,我们可以证明额叶网络与任务准备有关。进一步分析发现,中央前沟和额下沟交界处的额外侧皮层和前辅助运动区是任务准备过程中重要的额叶成分。
The ability to prepare a task is crucial for the voluntary control of our actions. It enables us to react flexibly and rapidly to a changing environment. In the present event-related functional magnetic resonance imaging study we investigated task preparation with a task-cueing paradigm. In this paradigm we intermixed trials in which a task cue and a target were presented with trials in which only the task cue was presented. Analysis of these cue-only trials allowed us to isolate task-preparation related control from execution-related control processes. By means of this paradigm, we could demonstrate that a frontal network was related to task preparation. Further analysis revealed that the fronto-lateral cortex at the junction of precentral sulcus and inferior frontal sulcus and the presupplementary motor area are the crucial frontal components in task preparation.