Cannabidiol: An overview of some pharmacological aspects

Cannabidiol: An overview of some pharmacological aspects
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DOI:
10.1002/j.1552-4604.2002.tb05998.x
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发表时间:
2002-11-01
影响因子:
2.9
通讯作者:
Gallily, R
Gallily, R
中科院分区:
医学4区
文献类型:
--
作者:
Mechoulam, R;Parker, LA;Gallily, R

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在过去的几年里,CBD的特性受到了相当大的关注。CBD不与已知的大麻二酚(CBD)一种主要的非精神药物成分大麻素受体结合,其作用机制尚不清楚。作者对化学未知进行了综述。有可能,至少在一定程度上,它的作用是由于CBD和抗惊厥,抗焦虑,它最近发现的抑制anandamide的摄取抗精神病,抗恶心,抗风湿性关节炎和水解,以及它的抗氧化作用。临床药理学杂志,2002。
Over the past few years, considerable attention has focused properties of CBD. CBD does not bind to the known on cannabidiol (CBD) a major nonpsychotropic constituent cannabinoid receptors, and its mechanism of action is yet of cannabis. The authors present a review on the chemistry unknown. It is possible that, in part at least, its effects are due of CBD and discuss the anticonvulsive, antianxiety, to its recently discovered inhibition of anandamide uptake antipsychotic, antinausea, and antirheumatoid arthritic and hydrolysis and to its antioxidative effect. Journal of Clinical Pharmacology, 2002.