Sex Differences in the Use of Statins in Community Practice Patient and Provider Assessment of Lipid Management Registry
Sex Differences in the Use of Statins in Community Practice Patient and Provider Assessment of Lipid Management Registry
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DOI：
10.1161/circoutcomes.118.005562
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发表时间：
2019-08-01
影响因子：
6.9
通讯作者：
Navar, Ann Marie
中科院分区：
文献类型：
--
作者：
Nanna, Michael G.;Wang, Tracy Y.;Navar, Ann Marie
背景：女性患者历来接受的血脂管理不如男性患者积极。目前的护理模式和这些差异的潜在原因尚不清楚。方法和结果：检查脂质管理登记处的患者和提供者评估（全国范围内患有动脉粥样硬化性心血管疾病或有风险的门诊患者登记处），我们比较了他汀类药物治疗的使用、指南推荐的他汀类药物剂量以及治疗不足的原因。我们使用多变量逻辑回归专门分析了他汀类药物治疗和指南推荐的他汀类药物剂量的性别差异。在 5693 名符合 2013 年美国心脏病学会/美国心脏协会胆固醇指南推荐的他汀类药物治疗资格的参与者（43% 女性）中，女性比男性接受任何他汀类药物治疗的可能性更低（67.0% 对比 78.4%；P
Background: Female patients have historically received less aggressive lipid management than male patients. Contemporary care patterns and the potential causes for these differences are unknown. Methods and Results: Examining the Patient and Provider Assessment of Lipid Management Registry-a nationwide registry of outpatients with or at risk for atherosclerotic cardiovascular disease-we compared the use of statin therapy, guideline-recommended statin dosing, and reasons for undertreatment. We specifically analyzed sex differences in statin treatment and guideline-recommended statin dosing using multivariable logistic regression. Among 5693 participants (43% women) eligible for 2013 American College of Cardiology/American Heart Association Cholesterol Guideline-recommended statin treatment, women were less likely than men to be prescribed any statin therapy (67.0% versus 78.4%; P