Sociocultural influences on attitudes towards pre-exposure prophylaxis (PrEP), history of PrEP use, and future PrEP use in HIV-vulnerable cisgender men who have sex with men across the U.S.
Sociocultural influences on attitudes towards pre-exposure prophylaxis (PrEP), history of PrEP use, and future PrEP use in HIV-vulnerable cisgender men who have sex with men across the U.S.
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DOI：
10.1891/lgbtq-2020-0005
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Grov C
中科院分区：
文献类型：
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作者：
Westmoreland DA;Patel VV;D'Angelo AB;Nash D;Grov C
尽管暴露前预防 (PrEP) 已被证明可以有效减少艾滋病毒传播，但其使用率仍然很低。本研究使用 2017-2018 年美国全国队列的数据来调查社会对男男性接触者的 PrEP 经历和未来 PrEP 使用的影响。我们使用描述性统计和多变量逻辑分析来检查与之前每次 PrEP 使用和使用 PrEP 意图相关的社会影响（例如，参与者如何听说 PrEP 以及他们认识的正在服用 PrEP 的人数）。在了解 PrEP 的参与者中，最常报告的首次听说 PrEP 的方式是通过社交媒体（27.4%）和朋友（26.8%）。这些也被认为是影响参与者当前对 PrEP 态度的主要因素（朋友 23.5%，社交媒体 22.1%）。多变量逻辑回归分析发现，了解更多正在服用 PrEP 的人与之前使用 PrEP 和打算使用 PrEP 的几率增加相关。朋友和社交媒体是有关 PrEP 的常见且有影响力的信息来源。结果表明，利用这些社会联系可以有效地传播有关 PrEP 的公共卫生信息，并鼓励重点人群使用以减轻艾滋病毒负担。
Despite its proven effectiveness in reducing HIV transmission, pre-exposure prophylaxis (PrEP) use remains low. This study used data from a 2017–2018 U.S. national cohort to investigate social influences on PrEP experience and future PrEP use among cisgender men who have sex with men. We used descriptive statistics and multivariable logistic analyses to examine social influences (e.g., how participants heard about PrEP and number of persons they knew taking PrEP) associated with each previous PrEP use and intentions to use PrEP. Among participants who knew of PrEP, commonly reported ways of first hearing about PrEP were through social media (27.4%) and friends (26.8%). These were also cited top influences on participants’ current attitudes toward PrEP (friends 23.5%, social media 22.1%). Multivariable logistic regression analyses found that knowing more people taking PrEP was associated with increased odds of previously using PrEP and intending to use PrEP. Friends and social media were common and influential sources of information regarding PrEP. Results suggest that tapping into these social connections may effectively disseminate public health messaging about PrEP and encourage use among key populations to reduce HIV burden.