Maternal carriage and neonatal colonisation of group B streptococcus in eastern Turkey:: prevalence, risk factors and antimicrobial resistance
Maternal carriage and neonatal colonisation of group B streptococcus in eastern Turkey:: prevalence, risk factors and antimicrobial resistance
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DOI：
10.1111/j.1368-5031.2005.00395.x
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发表时间：
2005-04-01
影响因子：
2.6
通讯作者：
Kadanali, S
中科院分区：
文献类型：
--
作者：
Kadanali, A;Altoparlak, Ü;Kadanali, S
我们的目的是确定孕妇中B族链球菌（GBS）携带的患病率、新生儿定植率和抗菌药物敏感性，以制定土耳其东部围产期GBS疾病的治疗和预防政策。总共有150名孕妇接受了GBS定殖筛查。从孕妇的阴道和直肠以及殖民母亲的新生儿的耳道、喉咙和脐部收集样品。还调查了分离株的抗菌药物敏感性。在48例病例中，150名妇女的至少一个标本中分离出GBS;据估计，总体而言，约32%的孕妇和17.3%的新生儿被GBS定殖。本研究中GBS垂直传播的总发生率为54.2%。当母亲年龄为20岁作为分界点时，母亲定植率在较年轻的年龄中显着较高（p < 0.01）。所有菌株对青霉素、氨苄西林、头孢唑啉和万古霉素均敏感。对红霉素和克林霉素的耐药率分别为13.5%和2.7%。
Our object is to determine the prevalence of group B streptococcus (GBS) carriage among pregnant women, the neonatal colonisation rate and the antimicrobial susceptibility to formulate a policy for treatment and prevention regarding perinatal GBS diseases in eastern Turkey. A total of 150 pregnant women were screened for GBS colonisation. Samples were collected from the vagina and the rectum of pregnant women, and the ear canal, throat and umbilicus of the neonates of colonised mothers. Antimicrobial susceptibility of the isolates was also investigated. GBS was isolated in at least one specimen from the 150 women in 48 cases; it was estimated that, overall, about 32% of the pregnant women and 17.3% of overall newborns were colonised with GBS. The overall rate of GBS vertical transmission was 54.2% in this study. Maternal colonisation rate was significantly higher in younger ages (p < 0.01) when maternal age of 20 years was taken as a cut-off point. All isolates were found to be sensitive to penicillin, ampicillin, cefazolin and vancomycin. Resistance to erythromycin and clindamycin were found to be 13.5 and 2.7%, respectively.