Victimization in Early Adolescence, Stress, and Depressive Symptoms Among Aging Sexual Minority Men: Findings from the Multicenter AIDS Cohort Study.
Victimization in Early Adolescence, Stress, and Depressive Symptoms Among Aging Sexual Minority Men: Findings from the Multicenter AIDS Cohort Study.
复制标题
老年性少数男性青春期早期的受害情况、压力和抑郁症状：多中心艾滋病队列研究的结果。
DOI：
10.1089/lgbt.2019.0036
复制
发表时间：
2020
期刊：
影响因子：
4.8
通讯作者：
Abraham,AlisonG
中科院分区：
文献类型：
--
作者：
Surkan,PamelaJ;Wang,Ruibin;Huang,Yuru;Stall,Ron;Plankey,Michael;Teplin,LindaA;Wight,RichardG;Jacobson,LisaP;Abraham,AlisonG
目的：我们调查的关系，在青春期早期的逆境和抑郁症的风险表型在成年后，以及是否在成年后的压力修改这些association.Methods：共1138名男性与男性发生性关系（MSM）参加了多中心艾滋病队列子研究，他们在青春期早期的逆境报告。Poisson回归估计了成年期逆境与抑郁表型之间关联的患病率（PR）。分层分析研究了过去一年中压力对抑郁表型的影响。结果：在调整后的模型中，受到言语侮辱的男性;受到身体暴力威胁的男性;向他们投掷物体的男性;或拳打脚踢或殴打的男性在成年后患抑郁表型的风险更高（每月≥1次与从不，PR = 1.50，95%置信区间[CI] = 1.15-1.96; PR = 1.84，95% CI = 1.45-2.34; PR = 2.00，95% CI = 1.51-2.66; PR = 1.78，95%CI = 1.35-2.34。被武器威胁接近统计学意义（PR = 1.89，95%CI = 0.96-3.72）。虽然更高的压力与抑郁症的整体，青少年早期受害只与抑郁症的男男性接触者没有报告在过去一年的高水平的压力（每月≥1次与从不，PR = 1.68，95% CI = 1.09-2.59; PR = 2.11，95% CI = 1.40-3.17; PR = 2.24，95% CI = 1.24-4.03; PR = 1.98，95%CI = 1.22-3.22）。结论：高应激男性的逆境与抑郁的关系减弱，这可能表明成年应激掩盖了早期青少年受害对成年抑郁的长期影响。青少年早期的受害可能会增加在中晚期生活中持续抑郁症状的风险，从而加强了预防策略的必要性。
Purpose:We investigated the relation between adversities in early adolescence and risk of a depressive phenotype in adulthood, and whether stress in adulthood modified these associations.Methods:A total of 1138 men who have sex with men (MSM) participated in a Multicenter AIDS Cohort substudy in which they reported on adversities in early adolescence. Poisson regression estimated prevalence ratios (PRs) for associations between adversities and a depressive phenotype in adulthood. Stratified analyses examined the effects of stress in the last year on the depressive phenotype.Results:In adjusted models, men who were verbally insulted; threatened by physical violence; had an object thrown at them; or punched, kicked, or beaten were at higher risk of having a depressive phenotype in adulthood (for ≥1 time per month vs. never, PR = 1.50, 95% confidence interval [CI] = 1.15–1.96; PR = 1.84, 95% CI = 1.45–2.34; PR = 2.00, 95% CI = 1.51–2.66; or PR = 1.78, 95% CI = 1.35–2.34, respectively.) Being threatened with a weapon approached statistical significance (PR = 1.89, 95% CI = 0.96–3.72). Although higher stress was associated with depression overall, early adolescent victimization was only associated with depression among MSM not reporting high levels of stress in the last year (for ≥1 time per month vs. never, PR = 1.68, 95% CI = 1.09–2.59; PR = 2.11, 95% CI = 1.40–3.17; PR = 2.24, 95% CI = 1.24–4.03; PR = 1.98, 95% CI = 1.22–3.22, respectively).Conclusion:The attenuation of relationships between adversities and depression among men reporting high stress may suggest that adult stress overshadows long-term effects of early adolescent victimization on adult depression. Victimization in early adolescence may increase the risk of sustained depressive symptoms in mid- to later life, reinforcing the need for preventive strategies.