Purely follicular mycosis fungoides without mucinosis: report of two cases with review of the literature.
Purely follicular mycosis fungoides without mucinosis: report of two cases with review of the literature.
复制标题
单纯性滤泡性蕈样肉芽肿不伴有粘蛋白沉积症：二例报道并文献复习。
DOI：
10.1067/mjd.2003.140
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发表时间：
2003
影响因子：
13.8
通讯作者：
G. Girolomoni
中科院分区：
文献类型：
--
作者：
Alessandro Monopoli;G. Annessi;G. Lombardo;G. Baliva;G. Girolomoni
滤泡病变可能与典型的斑块/斑块型蕈样真菌病有关，或者更罕见的是该病的唯一临床表现。我们描述了2例分别表现为脱发、弥散性毛囊性红斑丘疹、粉刺和囊肿的成年患者。在两例患者中，组织学显示在没有滤泡性黏液症的情况下，非典型淋巴细胞浸润于表皮。分子遗传学分析证实了t细胞浸润的寡聚/单克隆性质。报告病例纯滤泡性蕈样真菌病无黏液病。
Follicular lesions can either associate with typical patch-/plaque-type mycosis fungoides or, more rarely, be the only clinical manifestation of the disease. We describe 2 adult patients who presented with alopecia and disseminated follicular erythematous papules, and comedones and cysts, respectively. In both patients, histology showed a folliculotropic infiltrate of atypical lymphocytes that spared the epidermis, in the absence of follicular mucinosis. Molecular genetic analysis confirmed the oligo/monoclonal nature of the T-cell infiltrate. Reported cases of purely follicular mycosis fungoides without mucinosis are reviewed.