Palladium-catalyzed C-H homocoupling of bromothiophene derivatives and synthetic application to well-defined oligothiophenes.
Palladium-catalyzed C-H homocoupling of bromothiophene derivatives and synthetic application to well-defined oligothiophenes.
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DOI：
10.1021/ja060749v
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发表时间：
2006-07
影响因子：
15
通讯作者：
Masabumi Takahashi;K. Masui;Hiroki Sekiguchi;N. Kobayashi;A. Mori;M. Funahashi;N. Tamaoki
中科院分区：
文献类型：
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作者：
Masabumi Takahashi;K. Masui;Hiroki Sekiguchi;N. Kobayashi;A. Mori;M. Funahashi;N. Tamaoki
采用一种新的合成策略，利用溴噻吩的C-H均偶联和有机硅烷的交叉偶联，合成了具有2-8个噻吩单元的结构明确的低硫噻吩。碳溴键对钯催化的C-H均偶联的耐受性导致在噻吩环末端带有C-Br键的寡硫吩，这允许通过过渡金属配合物的催化进一步转化。
Synthesis of oligothiophenes of well-defined structures that possess 2-8 thiophene units is performed with a new synthetic strategy involving C-H homocoupling of bromothiophenes and cross-coupling with organostannanes. Tolerance of the carbon-bromine bond to the palladium-catalyzed C-H homocoupling results in oligothiophenes bearing C-Br bonds at the terminal thiophene rings, which allow further transformation by the catalysis of a transition-metal complex.