Self-Reported Hearing/Visual Loss and Mortality in Middle-Aged and Older Adults: Findings From the Komo-Ise Cohort, Japan
Self-Reported Hearing/Visual Loss and Mortality in Middle-Aged and Older Adults: Findings From the Komo-Ise Cohort, Japan
复制标题
DOI：
10.2188/jea.je20180198
复制
发表时间：
2020-02-01
影响因子：
4.7
通讯作者：
Kawachi, Ichiro
中科院分区：
文献类型：
--
作者：
Miyawaki, Atsushi;Kobayashi, Yasuki;Kawachi, Ichiro
背景：感觉丧失与死亡率的关系尚不清楚。我们的目的是探索听力损失(HL)、视力损失(VL)和双重感觉损失(DSL)与生存的关系。方法：数据来自日本群马县的KOMO-Ise研究队列。从1993年到2010年对40-69岁的社区居民进行了跟踪调查。我们分析了2000年9,522名受访者(2000年平均年龄[年龄47-77岁])。主要暴露为“仅HL”、“仅VL”或“DSL”，以“非HL/VL”为参照。这些感觉丧失状态是通过在2000年的跟踪调查问卷中询问在听对话或阅读报纸方面的困难，即使在有辅助的情况下进行的。通过与死亡证明数据的关联来确定所有原因和特定原因的死亡率。使用COX比例风险模型对混杂因素进行调整，包括人口因素、社会经济地位和健康状况。潜在的调节因素(抑郁、行走障碍和社会参与)被额外调整。结果：在10年的随访期中，有1105人死亡。在调整潜在混杂因素后，HL和DSL与全因死亡率增加相关(危险比分别为1.74[95%可信区间，1.18-2.57]和1.63[95%可信区间，1.09-2.42])。潜在的调解人解释了这种联系的一小部分。至于特定死因的死亡率。[IL与癌症死亡率增加相关，而VL和DSL与心血管疾病死亡率增加相关。结论：自我报告的HL和DSL可能是日本中老年人群死亡的危险因素。
Background: The association of sensory loss with mortality remains unclear. We aimed to explore the associations of hearing loss (HL), visual loss (VL), and dual sensory loss (DSL) with survival.Methods: Data came from the Komo-Ise study cohort in Gunma Prefecture, Japan. where the community-dwelling residents aged 40-69 years were followed up from 1993 to 2010. We analyzed 9,522 individuals who answered the follow-up questionnaires in 2000 (average age 64 [range, 47 to 77] years in 2000). The primary exposures were "HL only," "VL only," or "DSL", with "no HL/VL" as the reference. These sensory loss statuses were assessed by asking the difficulty in hearing conversation or reading newspaper even with aids in the follow-up questionnaires in 2000. All-cause and cause-specific mortality were ascertained from linkage to death certificate data. Cox proportional hazards models adjusting for confounders, including demographic factors, socioeconomic status, and health status, were used. Potential mediators (depression, walking disability, and social participation) were additionally adjusted for.Results: There were 1,105 deaths over the 10-year follow-up. After adjustment for the potential confounders, HL and DSL were associated with increased all-cause mortality (hazard ratios of 1.74 [95% CI, 1.18-2.57] and 1.63 [95% CI, 1.09-2.42], respectively). Potential mediators explained a modest portion of the association. As for cause-specific mortality. [IL was associated with increased cancer mortality, while VL and DSL were associated with increased cardiovascular disease mortality.Conclusions: Self-reported HL and DSL may be risk factors of mortality among middle-aged or elderly Japanese populations.