Population-based incidence of infection with selected bacterial enteric pathogens in children younger than five years of age, 1996-1998
Population-based incidence of infection with selected bacterial enteric pathogens in children younger than five years of age, 1996-1998
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DOI：
10.1097/01.inf.0000199289.62733.d5
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发表时间：
2006-02-01
影响因子：
3.6
通讯作者：
Vugia, DJ
中科院分区：
文献类型：
--
作者：
Koehler, KM;Lasky, T;Vugia, DJ
背景资料：以前的研究细菌性肠道感染已提出了一个不成比例的疾病负担的儿童年龄小于5岁的objectives.Objectives：这项研究描述了人口为基础的发病率培养证实感染6种细菌性肠道病原体的儿童年龄小于5岁的食源性疾病主动监测网络（FoodNet），1996- 1998年。通过在明尼苏达州、俄勒冈州和加州、康涅狄格州、格鲁吉亚、马里兰州和纽约的选定县进行的基于实验室的积极监测，确定了病例。21%（24，358人中的5，218人）的感染发生在5岁以下的儿童中，但这一年龄组仅占观察总人年的7%。在5岁以下的人群中，每种病原体的发病率（每10万人-年的病例数）为：沙门氏菌55.3例;弯曲杆菌43.4例;志贺氏菌32.7例;大肠杆菌O 157，10.3;小肠结肠炎耶尔森氏菌，7.1;单核细胞增生李斯特菌，0.7。发病率差异很大，7 FoodNet sites.Conclusions：这项研究证实了不成比例的疾病负担在幼儿。调查该年龄段特定的风险因素，审查和加强针对5岁以下儿童的当前预防和控制策略可能会减少疾病。
Background: Previous studies of bacterial enteric infections have suggested a disproportionate disease burden for children younger than 5 years of age.Objectives: This study describes population-based incidence of culture-confirmed infections with 6 bacterial enteric pathogens in children younger than 5 years of age in the Foodborne Diseases Active Surveillance Network (FoodNet), 1996-1998.Methods: Cases were ascertained through active laboratory-based surveillance in Minnesota, Oregon and selected counties in California, Connecticut, Georgia, Maryland and New York.Results: Twenty-one percent (5218 of 24,358) of infections were in children younger than 5 years of age, but this age group made up only 7% of the total person-years of observation. Among those younger than 5 years of age, the incidence (cases per 100,000 person-years) for each pathogen was: Salmonella, 55.3; Campylobacter, 43.4; Shigella, 32.7; E. coli O157, 10.3; Yersinia enterocolitica, 7.1; Listeria monocytogenes, 0.7. Incidence varied widely among the 7 FoodNet sites.Conclusions: This study confirmed a disproportionate disease burden in young children. Investigation of risk factors specific to this age group and review and enhancement Of Current prevention and control strategies for children younger than 5 years of age may reduce illness.