Radio frequency dual-spectra analysis of regional myocardial perfusion: Comparison with harmonic densitometric method.
Radio frequency dual-spectra analysis of regional myocardial perfusion: Comparison with harmonic densitometric method.
复制标题
局部心肌灌注的射频双谱分析：与谐波密度法的比较。
DOI：
10.1067/mje.2002.122967
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
M. Belohlavek
中科院分区：
文献类型：
--
作者：
T. Asanuma;B. Khandheria;J. Seward;M. Belohlavek
我们的目的是比较谐波-基频比峰值（HFRP）分析与传统的谐波灰度密度分析的基础上，消除超声信号的异质性的能力。在10只开胸猪中，在注入造影剂微泡之前和期间，通过使用间歇短轴扫描获得宽带射频和谐波数据。测量左室心肌6个节段的HFRP和灰阶强度值。在基线图像中，各向异性对HFRP值的影响显著小于灰度强度。在减影灌注评估中，HFRP值的对比度异质性显著小于灰度强度。减影后HFRP值的增加显著大于侧（P <0.001）、后（P <0.0001）和下（P <0.01）心肌的灰度强度。HFRP分析可以补偿基线心肌各向异性和局部对比度异质性。通过背景减除，HFRP分析可以更好地量化心肌灌注。
Our objective was to compare harmonic-to-fundamental frequency ratio peak (HFRp) analysis with conventional harmonic gray-scale densitometric analysis on the basis of ability to eliminate heterogeneity in ultrasound signals. Broadband radio frequency and harmonic data were obtained by using intermittent short-axis scans in 10 open-chest pigs before and during infusion of contrast microbubbles. HFRp and gray-scale intensity values were measured in 6 segments of left ventricular myocardium. In baseline images, the influence of anisotropy on HFRp values was significantly less than that in gray-scale intensities. In perfusion assessment with subtraction, contrast heterogeneity in HFRp values was significantly smaller than that in gray-scale intensities. The increase in HFRp values after subtraction was significantly greater than that in gray-scale intensities in lateral (P <.001), posterior (P <.0001), and inferior (P <.01) myocardium. HFRp analysis can compensate for baseline myocardial anisotropy and regional contrast heterogeneity. With background subtraction, HFRp analysis allows better quantification of myocardial perfusion.
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