Severe protein C deficiency in newborn infants.

Severe protein C deficiency in newborn infants.
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新生儿严重缺乏蛋白C。

DOI:
10.1016/s0022-3476(88)80284-1
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发表时间:
1988
期刊:
The Journal of pediatrics
影响因子:
--
通讯作者:
B. Warady
B. Warady
中科院分区:
--
文献类型:
--
作者:
M. Manco‐Johnson;M. Manco‐Johnson;Richard A. Martar;Richard A. Martar;L. Jacobson;L. Jacobson;T. Hays;T. Hays;B. Warady;B. Warady

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Eleven infants initially seen in the neonatal period had levels of protein C suggestive of homozygous protein C deficiency but as an apparently acquired condition. Family studies failed to document parental carrier status, the clinical course was not typical of that reported with homozygous protein C deficiency, and protein C levels increased in all restudied infants, six of whom received heparin anticoagulation. No infant had evidence of vitamin K deficiency. Care is advised in the evaluation of infants with low levels of protein C. Parental blood studies, delayed testing, and serial assays can help to establish the correct diagnosis.
严重的纯合蛋白 C 缺乏症。
DOI: 10.1016/s0022-3476(84)80013-x
发表时间: 1984
期刊: The Journal of pediatrics
影响因子: --
作者:
Sills,RH;Marlar,RA;Montgomery,RR;Deshpande,GN;Humbert,JR
通讯作者: Humbert,JR