Identification of a quorum sensing pheromone posttranslationally farnesylated at the internal tryptophan residue from Bacillus subtilis subsp. natto
Identification of a quorum sensing pheromone posttranslationally farnesylated at the internal tryptophan residue from Bacillus subtilis subsp. natto
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DOI：
10.1080/09168451.2015.1032884
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发表时间：
2015-10-03
影响因子：
1.6
通讯作者：
Okada, Masahiro
中科院分区：
文献类型：
--
作者：
Hayashi, Shunsuke;Usami, Syohei;Okada, Masahiro
枯草芽孢杆菌枯草亚种纳豆在群体感应的控制下产生聚γ-谷氨酸。我们确定了ComX（纳豆）信息素作为群体感应信息素的氨基酸序列的Lys-Trp-Pro-Pro-Ile-Glu和色氨酸残基后修饰法呢基基团。ComX（纳豆）信息素是独特的意义上，从C-末端的第5个色氨酸残基是法尼基化。
Bacillus subtilis subsp. natto produces poly-gamma-glutamic acid under the control of quorum sensing. We identified ComX(natto) pheromone as the quorum-sensing pheromone with an amino acid sequence of Lys-Trp-Pro-Pro-Ile-Glu and the tryptophan residue posttranslationally modified by a farnesyl group. ComX(natto) pheromone is unique in the sense that the 5th tryptophan residue from the C-terminal is farnesylated.