CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city
CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city
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DOI：
10.1007/s00330-020-06854-1
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发表时间：
2020-04-11
影响因子：
5.9
通讯作者：
Fu, Zhenming
中科院分区：
文献类型：
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作者：
Zhang, Rui;Ouyang, Huangqing;Fu, Zhenming
目的探讨严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)的胸部CT表现。比较普通与重症、有症状与无症状、发热与无热证患者的CT表现。方法对武汉市某三级医院2020年1月10日至2月10日收治的120例SARS-CoV-2肺炎患者的临床和胸部CT表现进行回顾性分析。结果入院时以发热、咳嗽、呼吸急促、肌肉酸痛或乏力为主诉，病情较重者易出现腹泻。重症患者平均年龄20岁，有合并症和乳酸脱氢酶(LDH)水平升高。根据中国国家卫生委员会的指南，无症状和有症状的普通型患者或无症状和发热的患者之间的CT表现没有差异。结论SARS-CoV-2肺炎患者入院时的临床和CT表现有助于及时评估患者的预后。临床医生应该意识到，临床上无症状的病例可能会表现出与有症状的普通患者相似的CT特征。
Objectives To characterize the chest computed tomography (CT) findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) according to clinical severity. We compared the CT features of common cases and severe cases, symptomatic patients and asymptomatic patients, and febrile and afebrile patients. Methods This was a retrospective analysis of the clinical and thoracic CT features of 120 consecutive patients with confirmed SARS-CoV-2 pneumonia admitted to a tertiary university hospital between January 10 and February 10, 2020, in Wuhan city, China. Results On admission, the patients generally complained of fever, cough, shortness of breath, and myalgia or fatigue, with diarrhea often present in severe cases. Severe patients were 20 years older on average and had comorbidities and an elevated lactate dehydrogenase (LDH) level. There were no differences in the CT findings between asymptomatic and symptomatic common type patients or between afebrile and febrile patients, defined according to Chinese National Health Commission guidelines. Conclusions The clinical and CT features at admission may enable clinicians to promptly evaluate the prognosis of patients with SARS-CoV-2 pneumonia. Clinicians should be aware that clinically silent cases may present with CT features similar to those of symptomatic common patients.