FINE PARTICULATE AIR POLLUTION AND HOSPITAL ADMISSIONS FOR ASTHMA: A CASE-CROSSOVER STUDY IN TAIPEI

FINE PARTICULATE AIR POLLUTION AND HOSPITAL ADMISSIONS FOR ASTHMA: A CASE-CROSSOVER STUDY IN TAIPEI
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DOI:
10.1080/15287394.2014.922387
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发表时间:
2014-01-01
影响因子:
2.6
通讯作者:
Yang, Chun-Yuh
Yang, Chun-Yuh
中科院分区:
医学4区
文献类型:
--
作者:
Cheng, Meng-Hsuan;Chen, Chih-Cheng;Yang, Chun-Yuh

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这项研究是为了确定台湾台北地区细颗粒物(PM2.5)水平与哮喘住院人数之间是否存在相关性。本研究取得台北市2006-2010年间因哮喘入院及环境空气污染的资料。采用病例交叉方法,控制天气变量、星期几、季节性和长期时间趋势,估计哮喘住院的相对风险。对于单污染物模型(没有调整其他污染物),在暖天(>23摄氏度)和凉天(<23摄氏度),哮喘入院人数的增加与PM2.5水平显著相关,四分位数范围内的上升分别与哮喘入院人数增加12%(95%CI=6-18%)和3%(95%CI=0-8%)相关。在双污染物模型中,PM2.5水平对于在温暖和凉爽的日子加入SO2或O-3后哮喘入院人数的增加仍然是显著的。这项研究提供的证据表明,在台湾,PM2.5水平较高会增加因哮喘入院治疗的风险。
This study was undertaken to determine whether there was a correlation between fine particles (PM2.5) levels and hospital admissions for asthma in Taipei, Taiwan. Hospital admissions for asthma and ambient air pollution data for Taipei were obtained for the period of 2006-2010. The relative risk of hospital admissions for asthma was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. For the single-pollutant model (without adjustment for other pollutants), increased asthma admissions were significantly associated with PM2.5 levels both on warm days (> 23 degrees C) and cool days (< 23 degrees C), with an interquartile range rise associated with a 12% (95% CI = 6-18%) and 3% (95% CI = 0-8%) elevation in admissions for asthma, respectively. In the two-pollutant models, PM2.5 levels remained significant for increased asthma admissions after inclusion of SO2 or O-3 both on warm and cool days. This study provides evidence that higher levels of PM2.5 elevate the risk of hospital admissions for asthma in Taiwan.