Tetrahedron beam imaging with a multi-pixel thermionic emission X-ray source and a photon-counting detector: A benchtop experimental study.
Tetrahedron beam imaging with a multi-pixel thermionic emission X-ray source and a photon-counting detector: A benchtop experimental study.
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DOI：
10.1002/mp.15211
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发表时间：
2021-11
期刊：
影响因子：
3.8
通讯作者：
Zhang T
中科院分区：
文献类型：
--
作者：
Chen Q;Zhou S;Tan Y;Hao Y;Zhang Z;Mazur T;Zhang T
具有彼此正交定位的线性X射线源阵列和线性检测器阵列的四面体射束（TB）X射线系统可以克服传统锥形射束X射线系统的X射线散射问题。我们开发了一个TB成像台式系统，使用线性阵列X射线源来演示TB成像的原理和优点。内部开发了一种多像素电子发射X射线（MPTEX）源，具有48个焦点，间距为4 mm。X射线束被准直成扇形束的堆叠，扇形束被会聚到6 mm宽的多行光子计数检测器（PCD）。通过移位相加算法将以固定视角对源进行顺序扫描收集的数据合成为2D射线照相图像。使用针对TB几何结构修改的基于FDK的CT算法，将系统完整旋转收集的数据重建为3D四面体束CT（TBCT）图像。TB台式系统具有18.8 cm长的源阵列和35 cm长的检测器阵列，提供25 cm横截面和8 cm轴向视场（FOV）。TB的散射-初级比（SPR）约为17%，而锥形束几何形状为120%。TBCT系统能够在二维X射线摄影和三维容积CT中进行重建。TBCT图像无“杯状”伪影，图像质量与诊断性螺旋CT相似。利用MPTEX光源和PCD成功研制了结核成像台式成像系统。体模和动物尸体成像证明，TB系统可以产生令人满意的X射线影像和3D CT影像，其影像质量与诊断螺旋CT相当。
A tetrahedron beam (TB) x-ray system with a linear x-ray source array and a linear detector array positioned orthogonal to each other may overcome the x-ray scattering problem of traditional cone-beam x-ray systems. We developed a TB imaging benchtop system using a linear array x-ray source to demonstrate the principle and benefits of TB imaging. A multi-pixel thermionic emission x-ray (MPTEX) source with 48 focal spots in 4 mm spacing was developed in-house. The x-ray beams are collimated to a stack of fan beams that are converged to a 6 mm wide multi-row photon-counting detector (PCD). The data collected with a sequential scan of the sources at a fixed view angle were synthesized to a 2D radiography image by a shift-and-add algorithm. The data collected with a full rotation of the system were reconstructed into 3D tetrahedron beam CT (TBCT) images using an FDK-based CT algorithm modified for the TB geometry. With an 18.8 cm long source array and a 35 cm long detector array, the TB benchtop system provides a 25 cm cross-sectional and 8 cm axial field of view (FOV). The scatter-to-primary ratio (SPR) was approximately 17% for TB, as compared with 120% for cone beam geometry. The TBCT system enables reconstructions in two-dimensional radiography and three-dimensional volumetric CT. The TBCT images were free of “cupping” artifacts and have similar image quality as diagnostic helical CT. A TB imaging benchtop imaging system was successfully developed with MPTEX source and PCD. Phantom and animal cadaver imaging demonstrated that the TB system can produce satisfactory radiographic x-ray images and 3D CT images with image quality comparable to diagnostic helical CTs.
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