Validation of the Restless Legs Syndrome Quality of Life questionnaire
Validation of the Restless Legs Syndrome Quality of Life questionnaire
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DOI：
10.1111/j.1524-4733.2005.03010.x
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发表时间：
2005-03-01
期刊：
影响因子：
4.5
通讯作者：
Earley, CJ
中科院分区：
文献类型：
--
作者：
Abetz, L;Vallow, SM;Earley, CJ
目的：采用《不宁腿综合征生活质量调查问卷》(RLSQoL)评估不宁腿综合征对日常生活、情感幸福感、社交生活和工作生活的影响。本研究考察了RLSQoL量表的效度和信度。方法：对85名美国原发RLS患者进行RLSQoL测试。结果：RLSQoL总分(范围0~100)具有良好的内部一致性信度(Cronbach‘sα=0.92)和重测信度(组内相关系数=0.84)。所有条目均显示可接受的条目收敛效度。RLSQoL分为轻、中、重度三组(F=52.22，P<；0.0001)。在2周内对RLS状态的改变(效应大小：改善，0.25；恶化，-0.32)显示出初步的反应性，表明在这段时间内，适度的尺度变化与微小的临床变化相一致。结论：这些发现支持RLSQoL的概念框架。它是RLS对QOL影响的有效和可靠的测量，并对症状严重程度的短期变化做出反应。RLSQoL似乎是以试验为基础的RLS治疗评估的合适工具。
Objectives: The Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) assesses the impact of RLS on daily life, emotional well-being, social life, and work life. This study investigates its validity and reliability.Methods: The RLSQoL was tested in 85 American adults with primary RLS. Patients were also asked to rate symptom severity with the International Restless Legs Scale (patient-reported version) and report on changes in symptoms over the 2-week period.Results: The RLSQoL summary scale score (range: 0-100) demonstrated acceptable internal consistency reliability (Cronbach's alpha = 0.92) and test-retest reliability (intraclass correlation coefficient = 0.84). All items indicated acceptable item-convergent validity. The RLSQoL distinguished between groups with mild, moderate, and severe symptoms (F = 52.22, P < 0.0001). It demonstrated preliminary responsiveness to changes in RLS status over 2 weeks (effect size: improvement, 0.25; deterioration, -0.32), indicating moderate scale changes consistent with the small clinical change over this time.Conclusions: These findings support the conceptual framework of the RLSQoL. It is a valid and reliable measure of the impact of RLS on QoL and is responsive to short-term changes in symptom severity. The RLSQoL appears to be an appropriate tool for trial-based assessments of treatments for RLS.