Assessment of uncertainty associated with measuring exposure to radon and decay products in the French uranium miners cohort
Assessment of uncertainty associated with measuring exposure to radon and decay products in the French uranium miners cohort
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DOI：
10.1088/0952-4746/32/1/85
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发表时间：
2012-03-01
影响因子：
1.5
通讯作者：
Laurier, Dominique
中科院分区：
文献类型：
--
作者：
Allodji, Rodrigue S.;Leuraud, Klervi;Laurier, Dominique
暴露数据的可靠性直接影响流行病学研究得出的风险估计的可靠性。在纠正测量不确定度之前，必须了解并理解测量不确定度。关于职业接触氡气（Rn-222）及其衰变产物的文献仅揭示了少数流行病学研究，其中明确考虑了不确定性。这项工作研究了法国铀矿矿工接触氡气 (Rn-222) 及其衰变产物的来源、性质、分布和不确定性程度。我们使用和方根 (RSS) 方法估计了该暴露的不确定性总大小，当无法进行重复测量时，这可能是一种替代方法。因此，我们确定了六个主要的不确定性来源。不确定性的总规模从1956-1974年期间的约47%下降到1982年后的10%，说明放射监测系统随着时间的推移而不断改进。
The reliability of exposure data directly affects the reliability of the risk estimates derived from epidemiological studies. Measurement uncertainty must be known and understood before it can be corrected. The literature on occupational exposure to radon (Rn-222) and its decay products reveals only a few epidemiological studies in which uncertainty has been accounted for explicitly. This work examined the sources, nature, distribution and magnitude of uncertainty of the exposure of French uranium miners to radon (Rn-222) and its decay products. We estimated the total size of uncertainty for this exposure with the root sum square (RSS) method, which may be an alternative when repeated measures are not available. As a result, we identified six main sources of uncertainty. The total size of the uncertainty decreased from about 47% in the period 1956-1974 to 10% after 1982, illustrating the improvement in the radiological monitoring system over time.