Histological Investigation of Polyethylene Particles in Total Hip Replacement: Ceramic versus Metal Heads
Histological Investigation of Polyethylene Particles in Total Hip Replacement: Ceramic versus Metal Heads
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全髋关节置换术中聚乙烯颗粒的组织学研究：陶瓷头与金属头
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
I. Bos
中科院分区：
文献类型：
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作者：
I. Bos
对128例翻修病例和40例尸检病例的陶瓷-金属聚乙烯假体周围的假包膜和界膜进行了组织形态学分析，包括磨损颗粒的半定量分级和组织学改变。磨损颗粒的数量随着植入时间的增加而增加。比较原位4 - 8年的金属-聚乙烯组合和陶瓷-聚乙烯组合的翻修病例，金属股骨头假体产生的聚乙烯磨损颗粒是金属股骨头假体的两倍多。在假体稳定的尸检病例中，聚乙烯磨损增加了3倍，金属-聚乙烯偶联的滑膜层更厚，滑膜表面的绒毛样转化和假囊的瘢痕样纤维化也更明显。除了双极假体外，不同类型的金属-聚乙烯组合假体之间的差异不明显，双极假体显示聚乙烯磨损明显增加。
Pseudocapsules and interface membranes around hip prostheses with ceramicand metal polyethylene combinations from 128 revision cases and 40 autopsy cases were histomorphologically analysed, including a semiquantitative grading of the wear particles and histological changes. The amount of wear particles increased with increasing implant duration. Comparing the revision cases with metal-on-polyethylene combinations and ceramic-on polyethylene combinations 4 to 8 years in situ, more than twice as many polyethylene wear particles were produced from prostheses with metallic heads. In the autopsy cases with stable prostheses 3 times more polyethylene wear was found. The synovial layer was found to be thicker in the metal-polyethylene couplings, the villous transformation of the synovial surface and the scar-like fibrosis of the pseudocapsules appeared to be more pronounced too. Differences between the different types of prostheses with metal-polyethylene combinations were not apparent with the exception of the bipolar prostheses, which showed markedly increased polyethylene wear.