Surgical failure following primary retinal detachment surgery by vitrectomy: risk factors and functional outcomes
Surgical failure following primary retinal detachment surgery by vitrectomy: risk factors and functional outcomes
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DOI：
10.1136/bjo.2010.190306
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发表时间：
2011-09-01
影响因子：
4.1
通讯作者：
Charteris, David G.
中科院分区：
文献类型：
--
作者：
Wickham, Louisa;Ho-Yen, Gregory O.;Charteris, David G.
目的：利用一项大型前瞻性随机对照试验中收集的数据，确定与玻璃体切除术后手术失败相关的术前特征。结果的患者谁再分离，然后检查在更detailed.Methods 615例患者进行了分析，作为一项随机对照试验的一部分，调查使用5-氟尿嘧啶和低分子量肝素。治疗状态对成功率没有影响，因此不构成分析的一部分。失败定义为初次玻璃体切除术后6个月内视网膜再脱离。采用单变量logistic回归分析评估失败与假定风险因素（年龄、病理性近视、眼内压、玻璃体出血、既往透镜摘除术、葡萄膜炎、视网膜象限脱离数量、视网膜裂孔数量和分布以及C级增生性玻璃体视网膜病变（PVR））之间的相关性。患者的其他特点，然后阐明，包括实现视网膜复位所需的操作，手术技术和最终logMAR visualacuity.Results 96例（15.6%）手术后再脱离，37失败，由于PVR。手术失败与视网膜象限脱离的数量相关（OR每增加一次，1.69（1.33 ~ 2.15）p
Aim To identify preoperative features associated with surgical failure following vitrectomy using data collected in a large, prospective randomised controlled trial. Outcomes of patients who redetached were then examined in more detail.Methods 615 patients were analysed as part of an randomised controlled trial investigating the use of 5-fluorouracil and low-molecular-weight heparin. Treatment status had no effect on success rates and did not therefore form part of the analyses. Failure was defined as retinal redetachment within 6 months of primary vitrectomy. Univariate logistic regression analysis was used to assess association between failure and putative risk factors (age, pathological myopia, intraocular pressure, vitreous haemorrhage, previous lens extraction, uveitis, number of retinal quadrants detached, number and distribution of retinal breaks, and grade C proliferative vitreoretinopathy (PVR)). Additional characteristics of patients were then elucidated including number of operations required to achieve retinal reattachment, surgical techniques used and final logMAR visual acuity.Results 96 patients (15.6%) redetached following surgery, and 37 failed due to PVR. Surgical failure was associated with number of retinal quadrants detached (OR per increase, 1.69 (1.33 to 2.15) p