Neuroleptic binding to human brain receptors: relation to clinical effects.

Neuroleptic binding to human brain receptors: relation to clinical effects.
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抗精神病药与人脑受体的结合:与临床效果的关系。

DOI:
10.1111/j.1749-6632.1988.tb42125.x
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发表时间:
1988
影响因子:
5.2
通讯作者:
Richelson,E
Richelson,E
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Richelson,E

文献摘要

被引文献

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表2总结了神经阻滞剂阻断神经递质受体的潜在临床后果。抗精神病药在大脑和身体其他部位的受体上的这些药理作用可能是治疗和某些不良反应以及一些药物相互作用的原因。这里提供的数据应允许医生选择神经抑制剂,以尽量减少这些不必要的影响,在病人的合理基础。
Table 2 summarizes the potential clinical consequences of neurotransmitter receptor blockade by neuroleptics. These pharmacological effects of neuroleptics at receptors in brain and elsewhere in the body are likely responsible for therapeutic and certain adverse effects as well as some drug-drug interactions. Data presented here should allow the physician a rational basis for selecting neuroleptics to minimize these unwanted effects in patients.