Enhanced Hydrolytic Resistance of Fluorinated Silicon-Containing Polyether Urethanes
Enhanced Hydrolytic Resistance of Fluorinated Silicon-Containing Polyether Urethanes
复制标题
氟化含硅聚醚聚氨酯的增强耐水解性
DOI：
10.1021/acs.biomac.9b01768
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发表时间：
2020
影响因子：
6.2
通讯作者：
Fu Qiang
中科院分区：
文献类型：
--
作者：
Li Yaomin;Yuan Lei;Ming Hao;Li Xin;Tang Lin;Zhang Jian;Wang Ruichen;Wang Gang;Jiang Yan;Li Zhen;Luo Feng;Li Jiehua;Tan Hong;Fu Qiang
以聚二甲基硅氧烷（PDMS）为第二大二醇，氟化二醇（FDO）为另一扩链剂，在70℃的缓冲溶液中浸泡，研究了新合成的聚醚型聚氨酯（PEU）的水解反应。通过扫描电镜（SEM）、凝胶渗透色谱（GPC）和拉伸测试来监测水解过程。老化32周后，氟化含硅peu （FSPEU）表面未见缺陷。同时，FDO的加入并没有改变体积水解的其他问题，如分子量和机械强度的变化。此外，在温度加速水解过程中，FSPEU的微相分离受到抑制，而由于氟化侧链的阻碍作用，老化导致硅修饰peu （SPEU）的形态变化更为明显。在FDO的存在下，易水解的阿尔法酸盐的形成也会减少。FSPEU具有增强的抗水解性能，可以潜在地应用于生物稳定的医疗设备。
The hydrolysis of a newly synthesized polyether urethane (PEU) that uses polydimethylsiloxane (PDMS) as a second macrodiol and fluorinated diol (FDO) as another chain extender has been studied via immersion in buffer solutions at 70 °C. The hydrolysis process was monitored using scanning electron microscopy (SEM), gel permeation chromatography (GPC), and tensile testing. After aging for 32 weeks, no surface defect was observed on the fluorinated silicon-containing PEUs (FSPEU). Meanwhile, the addition of FDO did not alter the other issues of bulk hydrolysis, such as the changes in molecular weight and mechanical strength. Moreover, microphase separation of FSPEU was suppressed during temperature-accelerated hydrolysis, whereas aging induced a more noticeable phase of morphological change in silicon-modified PEUs (SPEU) due to the hindrance effect of the fluorinated side chains. The formation of hydrolysis-prone allophanate is also reduced in the presence of FDO. FSPEU with enhanced antihydrolysis performance can potentially be applied to biostable medical devices.