A unique late-replicating XY to autosome translocation in Peromyscus melanophrys.
A unique late-replicating XY to autosome translocation in Peromyscus melanophrys.
复制标题
Peromyscus melanophrys 中独特的晚期复制 XY 至常染色体易位。
DOI：
10.1007/s10577-010-9113-3
复制
发表时间：
2010
期刊：
影响因子：
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通讯作者：
O'Neill,RachelJ
中科院分区：
文献类型：
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作者：
Mlynarski,ElisabethE;Obergfell,Craig;Dewey,MichaelJ;O'Neill,RachelJ
We report on the characterization of thePeromyscus melanophryskaryotype and sex chromosome system. Classic studies reported the sex chromosome system of this species may be as complex as an X1X1X2X2/X1X2Y1Y2and provided conflicting identification of the X chromosome. UsingPeromyscus maniculatuschromosome paints, we have positively identified the sex chromosomes and clarified the sex determining system that once perplexedPeromyscusresearchers. The sex chromosomes are characterized by a unique autosomal translocation of DNA shared between both the X and Y chromosomes. The translocated material is late replicating and heterochromatic yet retains the active chromatin conformation. Thus, autosomal regions derived from translocations involving repeat-rich material may retain some epigenetic marks specific to the sex chromosomes despite loss of epigenetic silencing activity.
