Compilation of a standardised international folate database for EPIC
Compilation of a standardised international folate database for EPIC
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DOI：
10.1016/j.foodchem.2014.11.044
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发表时间：
2016-02-15
期刊：
影响因子：
8.8
通讯作者：
Slimani, Nadia
中科院分区：
文献类型：
--
作者：
Nicolas, Genevieve;Witthoft, Cornelia M.;Slimani, Nadia
本文介绍了“国际最终用户”叶酸数据库的编制方法。这项工作得益于欧洲癌症和营养前瞻性调查(EPIC)提供的独特数据集(N=23个中心的52万名受试者)。汇编分四个步骤完成：(1)确定无叶酸食物，然后找出(2)在史诗国家普遍存在的富含叶酸的食物，(3)剩余的“常见”食物，以及(4)“特定国家的”食物。利用国家食品成分表(FCT)中的信息，同时在单位、表达方式和化学分析方面对汇编的叶酸值进行标准化。总叶酸值的43-70%由微生物测定法记录。EPIC中报告的食物要么直接与FCT食物匹配，作为食谱处理，要么作为加权平均处理。这项工作产生了欧洲第一个标准化的叶酸数据集，用于计算EPIC中的叶酸摄入量；这是研究叶酸摄入量与疾病关系的先决条件。(C)爱思唯尔有限公司出版的2014年。
This paper describes the methodology applied for compiling an "international end-user'' folate database. This work benefits from the unique dataset offered by the European Prospective Investigation into Cancer and Nutrition (EPIC) (N = 520,000 subjects in 23 centres). Compilation was done in four steps: (1) identify folate-free foods then find folate values for (2) folate-rich foods common across EPIC countries, (3) the remaining "common'' foods, and (4) "country-specific'' foods. Compiled folate values were concurrently standardised in terms of unit, mode of expression and chemical analysis, using information in national food composition tables (FCT). 43-70% total folate values were documented as measured by microbiological assay. Foods reported in EPIC were either matched directly to FCT foods, treated as recipes or weighted averages. This work has produced the first standardised folate dataset in Europe, which was used to calculate folate intakes in EPIC; a prerequisite to study the relation between folate intake and diseases. (C) 2014 Published by Elsevier Ltd.