CURING OF A KILLER FACTOR IN SACCHAROMYCES-CEREVISIAE
CURING OF A KILLER FACTOR IN SACCHAROMYCES-CEREVISIAE
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DOI：
10.1073/pnas.69.10.2846
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发表时间：
1972-01-01
影响因子：
11.1
通讯作者：
STYLES, CA
中科院分区：
文献类型：
--
作者：
FINK, GR;STYLES, CA
许多标准实验室储备的酵母能够杀死其他酵母菌株。这一特性尚未得到普遍认可，因为仅在低pH下观察到杀灭作用，而在标准培养基的pH下未观察到。在所有的菌株中，杀手性状的遗传决定因素显示非孟德尔遗传。我们的杀手菌株的分离模式表明，这个杀手决定因素可能不同于以前描述的杀手。用放线菌酮而不是溴化乙锭处理杀伤菌株，可将其转化为敏感的非杀伤菌株。
Many standard laboratory stocks of yeast are able to kill other yeast strains. This property has not been generally recognized because killing is observed only at low pH and not at the pH of standard media. In all strains examined, the genetic determinant for the killer trait shows non-Mendelian inheritance. The segregation patterns of our killer strains indicate that this killer determinant may be different from the killer previously described. Treatment of a killer strain with cycloheximide, but not with ethidium bromide, converts it into a sensitive nonkiller.