Electrocatalytic multicomponent assembling of phthalhydrazide, aldehydes and malononitrile: An efficient approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones
Electrocatalytic multicomponent assembling of phthalhydrazide, aldehydes and malononitrile: An efficient approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones
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邻苯二甲酰肼、醛和丙二腈的电催化多组分组装：制备 1H-吡唑并[1,2-b]酞嗪-5,10-二酮的有效方法
DOI：
10.1016/j.crci.2013.09.017
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
A. Delafrooz
中科院分区：
文献类型：
--
作者：
H. Kefayati;Shadi Homayoon Amlashi;Reyhaneh Kazemi;A. Delafrooz
以溴化钠为电解质，邻苯二甲酰肼、芳香醛和丙二腈为原料，在无隔膜电解槽中，于室温下电催化多组分转化反应，得到1H-吡唑并[1，2-B]酞嗪-5，10-二酮，反应时间短（4-8 min），产率高（85-98%）。开发的有效的电催化方法，相应的1 H-吡唑并[1，2-B]酞嗪-5，10-二酮是有益的，从多样性为导向的大规模过程的观点，并代表了一个新的例子，生态纯的合成概念的电催化多组分反应策略。
Electrocatalytic multicomponent transformation of phthalhydrazide, aromatic aldehydes and malononitrile in n-propanol in an undivided cell in the presence of sodium bromide as an electrolyte leads to 1 H-pyrazolo [1, 2-b] phthalazine-5, 10-diones in short reaction times (4–8 min) and high yields (85–98%) at room temperature. The developed efficient electrocatalytic approach to the corresponding 1 H-pyrazolo [1, 2-b] phthalazine-5, 10-diones is beneficial from the viewpoint of diversity-oriented large-scale processes and represents a new example of the ecologically pure synthetic concept for electrocatalytic multicomponent reactions strategy.