Patient-Specific Three-Dimensional Concomitant Dose From Cone Beam Computed Tomography Exposure in Image-Guided Radiotherapy
Patient-Specific Three-Dimensional Concomitant Dose From Cone Beam Computed Tomography Exposure in Image-Guided Radiotherapy
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DOI：
10.1016/j.ijrobp.2011.06.1972
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发表时间：
2012-05-01
影响因子：
7
通讯作者：
Staffurth, John
中科院分区：
文献类型：
--
作者：
Spezi, Emiliano;Downes, Patrick;Staffurth, John
目的：本研究的目的是量化在不同临床情况下接受锥形束计算机断层扫描 (CBCT) 扫描的患者所接受的伴随剂量，作为图像引导放射治疗 (IGRT) 程序的一部分。方法和材料：我们计算了代表不同临床情况的 6 名患者接受 CBCT 扫描的三维伴随剂量：两个骨盆、两个头部 和脖子，还有两个胸部。我们评估了每日在线 IGRT 策略对患者剂量分布的影响，假设在整个治疗过程中进行 40 次 CBCT 扫描。还估计了计划目标体积边缘区域的额外剂量。结果：在骨盆中，单次 CBCT 扫描向股骨头和直肠传递的平均剂量为 2-6 cGy 和 1-2 cGy。计划目标体积的额外剂量在 1 -3 cGy 以内。在胸部，计划目标体积的平均剂量从 2.5 到 5 cGy 不等。收到的处于危险中的肺和脊髓计划器官体积
Purpose: The purpose of the present study was to quantify the concomitant dose received by patients undergoing cone beam computed tomography (CBCT) scanning in different clinical scenarios as a part of image-guided radiotherapy (IGRT) procedures.Methods and Materials: We calculated the three-dimensional concomitant dose received as a result of CBCT scans in 6 patients representing different clinical scenarios: two pelvis, two head and neck, and two chest. We assessed the effect that a daily on-line IGRT strategy would have on the patient dose distribution, assuming 40 CBCT scans throughout the treatment course. The additional dose to the planning target volume margin region was also estimated.Results: In the pelvis, a single CBCT scan delivered a mean dose to the femoral heads of 2-6 cGy and the rectum of 1-2 cGy. An additional dose to the planning target volume was within 1 -3 cGy. In the chest, the mean dose to the planning target volume varied from 2.5 to 5 cGy. The lung and spinal cord planning organ at risk volume received