Vestibular perception and action employ qualitatively different mechanisms.: II.: VOR and perceptual responses during combined Tilt&Translation
Vestibular perception and action employ qualitatively different mechanisms.: II.: VOR and perceptual responses during combined Tilt&Translation
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DOI：
10.1152/jn.00905.2004
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发表时间：
2005-07-01
影响因子：
2.5
通讯作者：
Wood, S
中科院分区：
文献类型：
--
作者：
Merfeld, DM;Park, S;Wood, S
为了比较和对比的神经机制，前庭知觉和行动，我们测量前庭眼反射（VOR）和倾斜和平移的看法。我们利用了众所周知的模糊性，即耳石器官对重力的线性加速度和倾斜都有反应，并研究了解决这种模糊性的机制。使用了一种新的运动范例，结合滚转倾斜与耳间平移（“平移和平移”）;受试者正弦（0.8 Hz）滚转倾斜，但他们的耳朵高于或低于旋转轴。这种模式提供了正弦滚动运河线索，是相同的试验，而提供耳石线索，耳位置相对于地球水平旋转轴线性变化。我们发现，感知倾斜和翻译依赖于运河线索，大量的滚动倾斜和耳间翻译的看法，即使耳石器官测量没有耳间的力量。这些发现符合内部模型预测，从运河的旋转线索影响耳石线索的神经处理。我们还发现，水平平移VOR随半径呈线性变化;当耳石器官转导很少或没有耳间力时，测量到最小的响应。因此，水平平移VOR依赖于耳石线索，但独立于运河线索。这些发现与翻译VOR是由耳石信号的简单过滤引起的预测相匹配。我们的结论是，内部模型支配人类感知的倾斜和平移在0.8 Hz，高通滤波支配人类平移VOR在同一频率。
To compare and contrast the neural mechanisms that contribute to vestibular perception and action, we measured vestibuloocular reflexes (VOR) and perceptions of tilt and translation. We took advantage of the well-known ambiguity that the otolith organs respond to both linear acceleration and tilt with respect to gravity and investigated the mechanisms by which this ambiguity is resolved. A new motion paradigm that combined roll tilt with inter-aural translation ("Tilt&Translation") was used; subjects were sinusoidally (0.8 Hz) roll tilted but with their ears above or below the rotation axis. This paradigm provided sinusoidal roll canal cues that were the same across trials while providing otolith cues that varied linearly with ear position relative to the earth-horizontal rotation axis. We found that perceived tilt and translation depended on canal cues, with substantial roll tilt and inter-aural translation perceptions reported even when the otolith organs measured no inter-aural force. These findings match internal model predictions that rotational cues from the canals influence the neural processing of otolith cues. We also found horizontal translational VORs that varied linearly with radius; a minimal response was measured when the otolith organs transduced little or no inter-aural force. Hence, the horizontal translational VOR was dependent on otolith cues but independent of canal cues. These findings match predictions that translational VORs are elicited by simple filtering of otolith signals. We conclude that internal models govern human perception of tilt and translation at 0.8 Hz and that high-pass filtering governs the human translational VOR at this same frequency.