Relation between low calcium intake, parathyroid hormone, and blood pressure

Relation between low calcium intake, parathyroid hormone, and blood pressure
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DOI:
10.1161/01.hyp.35.5.1154
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发表时间:
2000-05-01
期刊:
影响因子:
8.3
通讯作者:
Bonaa, KH
Bonaa, KH
中科院分区:
医学1区
文献类型:
--
作者:
Jorde, R;Sundsfjord, J;Bonaa, KH

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在1995年的一项人口健康调查中,测量了1113名年龄在30至79岁之间的受试者的血清甲状旁腺激素(PTH),发现118名受试者的血清甲状旁腺激素(PTH)升高(>6.9 pmol/L)。1998年,这一组和131名PTH水平正常的受试者被邀请进行复查,分别有82名和90名受试者参加了随访。随访时,72例受试者血清PTH水平升高,100例血清PTH水平正常。血清甲状旁腺素水平升高者(排除8例甲状旁腺功能亢进者)血清钙水平和钙摄入量显著低于正常者(分别为2.24 ± 0.09和3.29 ± 0.10 mmol/L [平均值± SD]和400.3 ± 227.3和592.1 ± 459.6 mg/d; P
In a population health survey in 1995, serum parathyroid hormone (PTH) was measured in 1113 subjects, aged 30 to 79 years, and was found to be elevated (>6.9 pmol/L) in 118 subjects. In 1998, this group and 131 subjects with normal PTH levels were invited for reexamination, and 82 and 90 subjects from each respective group attended the follow-up. At the follow-up, 72 subjects had elevated and 100 had normal serum PTH levels. Those with elevated serum PTH levels (8 subjects with hyperparathyroidism were excluded) had significantly lower serum calcium levels and intake of calcium than those with normal PTH (2.24+/-0.09 and 3.29+/-0.10 mmol/L [mean+/-SD] and 400.3+/-227.3 and 592.1+/-459.6 mg/d, respectively; P