Process of Progression of Coronary Artery Lesions From Mild or Moderate Stenosis to Moderate or Severe Stenosis
Process of Progression of Coronary Artery Lesions From Mild or Moderate Stenosis to Moderate or Severe Stenosis
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冠状动脉病变由轻、中度狭窄发展为中、重度狭窄的过程
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
HisayoshiFujiwara
中科院分区：
文献类型：
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作者：
KoichiYokoya;HisatoTakatsu;TakahikoSuzuki;HiroakiHosokawa;ShinsukeOjio;TetsuoMatsubara;TsutomuTanaka;SachiroWatanabe;NorihikoMorita;KazuhikoNishigaki;GenzouTakemura;ToshiyukiNoda;ShinyaMinatoguchi;HisayoshiFujiwara
背景-冠状动脉疾病的进展过程尚不清楚。方法和结果：研究对象为36例有36条客观血管的患者，这些患者的冠状动脉疾病进展具有临床意义（每年≥15%），在1年的时间内，每隔14个月进行4次连续冠状动脉造影（CAG）。2个连续CAG之间的狭窄百分比进展程度分为显著（M：≥15%）、轻度（S：5%至14%）和无进展（N：<5%）。根据病变进展类型，36支血管分为14支明显进展的1型血管（13支血管N→N→M，1支血管S→S→M）和22支无明显进展的2型血管（18支血管S→S，4支血管N→S→S）。1型血管在第一次、第二次、第三次和最终CAG时的狭窄百分比分别为44± 14%、46 ± 13%、46± 13%和88±10%（与第一次CAG相比P<0.05），2型血管为44± 11%、50± 9%、59± 9%和67±9%（与第一次CAG相比，第二次、第三次和最终CAG的狭窄百分比P<0.05）。1型船舶费...
Background—The process of progression in coronary artery disease is unknown. Methods and Results—The subjects were 36 patients with 36 objective vessels with clinically significant progression of coronary artery disease (≥15% per year) in whom 4 serial coronary arteriograms (CAGs) were performed at intervals of ≈4 months in a 1-year period. The degree of progression of percent stenosis between each of 2 serial CAGs was classified as marked (M: ≥15%), slight (S: 5% to 14%), and no progression (N: <5%). From the pattern of progression, the 36 vessels were classified as 14 type 1 vessels with marked progression (N→N→M in 13 vessels and S→S→M in 1 vessel) and 22 type 2 vessels without marked progression (S→S→S in 18 vessels, N→S→S in 4). Percent stenosis at the first, second, third, and final CAGs was 44±14%, 46±13%, 46±13%, and 88±10% (P<0.05 versus first CAG) in type 1 vessels and 44±11%, 50±9%, 59±9%, and 67±9% in type 2 vessels (P<0.05 for second, third, and final CAGs versus first CAG). Type 1 vessels fe...