Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects.
Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects.
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DOI：
10.3390/biomedicines10071712
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发表时间：
2022-07-15
期刊：
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
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作者：
纤维蛋白原(Fg)及其衍生物在许多疾病中发挥着重要作用。例如，在许多炎症性疾病中，如阿尔茨海默病、多发性硬化症、创伤性脑损伤、类风湿性关节炎、系统性红斑狼疮和癌症，都发现FG水平升高。尽管FG、FG链及其衍生物与各种疾病的关系已经建立，但它们的具体作用和作用机制仍不清楚。本文首次对FG、FG链及其衍生物和FG家族其他成员，如FG样蛋白1和2在炎症性疾病中的作用及其在免疫调节中的作用进行了综述。
Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid arthritis, systemic lupus erythematosus, and cancer. Although associations of Fg, Fg chains, and its derivatives with various diseases have been established, their specific effects and the mechanisms of actions involved are still unclear. The present review is the first attempt to discuss the role of Fg, Fg chains, its derivatives, and other members of Fg family proteins, such as Fg-like protein 1 and 2, in inflammatory diseases and their effects in immunomodulation.
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影响因子：
16.2
作者：
Cortes-Canteli, Marta;Paul, Justin;Norris, Erin H.;Bronstein, Robert;Ahn, Hyung Jin;Zamolodchikov, Daria;Bhuvanendran, Shivaprasad;Fenz, Katherine M.;Strickland, Sidney
通讯作者：
Strickland, Sidney
影响因子：
16.6
作者：
通讯作者：
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影响因子：
8.3
作者：
del Zoppo GJ;Levy DE;Wasiewski WW;Pancioli AM;Demchuk AM;Trammel J;Demaerschalk BM;Kaste M;Albers GW;Ringelstein EB
通讯作者：
Ringelstein EB
影响因子：
2.5
作者：
Charkviani, Mariam;Muradashvili, Nino;Lominadze, David
通讯作者：
Lominadze, David
DOI：
10.1046/j.1365-2362.2002.00994.x
发表时间：
2002-05-01
影响因子：
5.5
作者：
Fiala, M;Liu, QN;Vinters, HV
通讯作者：
Vinters, HV