A simple and efficient phosphorescent probe for iodide-specific detection based on crystallization-induced phosphorescence of organic ionic crystals
A simple and efficient phosphorescent probe for iodide-specific detection based on crystallization-induced phosphorescence of organic ionic crystals
复制标题
一种简单高效的磷光探针，用于基于有机离子晶体结晶诱导磷光的碘化物特异性检测
DOI：
10.1039/c8tc04781b
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发表时间：
2019
影响因子：
6.4
通讯作者：
Qian Zhaosheng
中科院分区：
文献类型：
--
作者：
Chen Guilin;Zhou Jin;Feng Hui;Feng Feifei;Xu Pengfei;Pan Saifei;Xu Jing;Qian Zhaosheng
碘离子的重原子效应会导致一般荧光团的荧光猝灭，因此发展碘离子的荧光检测方法具有很大的挑战性。在这里，我们揭示了一个独特的结晶诱导明亮的磷光四苯基碘化磷（TPP I）和发展一种新的时间门控检测方法的碘离子，以尽量减少自发荧光从复杂的生物样品。重碘离子和易接近的离子相互作用诱导的有机晶体的参与有助于TPP I实现非常高的磷光量子产率（0.42）。这种特定的碘化物触发的明亮的有机磷光使得能够以发光开启方式开发用于碘离子的新型时间门控检测方法，并且进一步提供了建立基于固体基质上的固态磷光的用于碘离子的视觉检测的简易测试条的机会。该探针在活细胞碘离子成像中的优异性能以及在双重加密中的有趣应用说明了高效有机离子晶体在各个领域的通用性和广阔的应用前景。
It is very challenging to develop luminescent detection methods for iodide ions due to their significant fluorescence quenching of general fluorophores induced by the heavy-atom effect. Herein, we reveal a unique crystallization-induced bright phosphorescence of tetraphenylphosphonium iodide (TPP I) and develop a novel time-gated detection method for iodide ions to minimize the autofluorescence from complex biological samples. Both the involvement of heavy iodide ion and accessible ionic interaction-induced organic crystals contribute to the accomplishment of a very high phosphorescence quantum yield (0.42) for TPP I. This specific iodide-triggered bright organic phosphorescence enables the development of a novel time-gated detection method for iodide ions in the luminescence turn-on manner and further offers an opportunity to establish a facile test strip for the visual detection of iodide ions based on solid-state phosphorescence on a solid substrate. Excellent performance of this probe in imaging iodide in live cells and intriguing use in double encryption illustrate the versatile and broad application prospects of highly efficient organic ionic crystals in various areas.