THE STATE OF NEUTRAL LIPIDS IN NORMAL AND CATARACTOUS HUMAN LENSES
THE STATE OF NEUTRAL LIPIDS IN NORMAL AND CATARACTOUS HUMAN LENSES
复制标题
DOI：
10.1016/0014-4835(83)90153-7
复制
发表时间：
1983-01-01
影响因子：
3.4
通讯作者：
SPECTOR, A
中科院分区：
文献类型：
--
作者：
DILLON, J;MEHLMAN, B;SPECTOR, A
开发了一种简单快速的高压液相色谱方法（HPLC）来分析正常和白内障人类晶状体中的中性脂质部分。旧的正常晶状体和白内障晶状体之间没有发现差异，这表明白内障中的膜退化不是由于这些成分的氧化造成的。分离并鉴定了几种新的晶状体成分，包括胆固醇代谢物和维生素E（α-生育酚）。
A simple and rapid high pressure liquid chromatographic method (HPLC) was developed to analyze the neutral lipid fraction from normal and cataractous human lenses. No differences were found between old normal and cataractous lenses suggesting that membrane deterioration in cataracts is not due to oxidation of these components. Several new lens components were isolated and identified including cholesterol metabolites and vitamin E (.alpha.-tocopherol).