Individual-based Modeling of Genome Evolution in Haplodiploid Organisms.

Individual-based Modeling of Genome Evolution in Haplodiploid Organisms.
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基于个体的单倍二倍体生物基因组进化建模。

DOI:
10.1093/gbe/evac062
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发表时间:
2022-05-03
影响因子:
3.3
通讯作者:
Wurm, Yannick
Wurm, Yannick
中科院分区:
生物学2区
文献类型:
--
作者:
Pracana, Rodrigo;Burns, Richard;Hammond, Robert L.;Haller, Benjamin C.;Wurm, Yannick

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蚂蚁、蜜蜂、黄蜂、树皮甲虫和其他物种都有单倍体雄性和二倍体雌性。虽然这样的单倍二倍体物种发挥关键的生态作用,并受到环境变化的威胁,没有一般的框架存在模拟其遗传进化。在这里,我们使用SLiM模拟环境,建立一个新的模型,基于个体的遗传进化的正向模拟在单倍二倍体。我们比较了适应性突变和有害突变的命运,发现对隐性突变的选择在单倍体二倍体中比在二倍体中更有效。我们的开源模型将促进对社会性进化的理解,以及生态上重要的单倍二倍体物种如何应对不断变化的环境。
Ants, bees, wasps, bark beetles, and other species have haploid males and diploid females. Although such haplodiploid species play key ecological roles and are threatened by environmental changes, no general framework exists for simulating their genetic evolution. Here, we use the SLiM simulation environment to build a novel model for individual-based forward simulation of genetic evolution in haplodiploids. We compare the fates of adaptive and deleterious mutations and find that selection on recessive mutations is more effective in haplodiploids than in diploids. Our open-source model will foster an understanding of the evolution of sociality and how ecologically important haplodiploid species may respond to changing environments.
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影响因子: 10.7
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