Naloxone perspectives from people who use opioids: Findings from an ethnographic study in three states.
Naloxone perspectives from people who use opioids: Findings from an ethnographic study in three states.
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DOI：
10.1097/jxx.0000000000000371
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发表时间：
2020-04-01
影响因子：
1.2
通讯作者：
Lamonica AK
中科院分区：
文献类型：
--
作者：
Boeri M;Lamonica AK
纳洛酮是一种阿片类药物拮抗剂，可以逆转阿片类药物过量。阿片类药物相关死亡率的增加导致纳洛酮在没有处方的情况下的分布和非专业人士服用纳洛酮的增加。这项研究填补了居住在郊区社区的阿片类药物活跃使用者对纳洛酮体验的了解空白。本文的目的是让执业护士 (NP) 深入了解目前对经历过药物过量事件的患者使用纳洛酮的做法。具体目标是比较不同郊区城镇对纳洛酮的获取情况，检查不同环境下的管理差异，并了解积极使用阿片类药物的人对纳洛酮体验的看法。这项分析的数据来自于佐治亚州亚特兰大周边郊区城镇的一项人种学研究；马萨诸塞州波士顿；和康涅狄格州纽黑文。收集了简短的调查和深入的访谈。归纳方法用于比较不同设置的数据。 106 名样本中包括 48% 女性、62% 白人、24% 非裔美国人/黑人、13% 多于一种种族、21% 西班牙裔/拉丁裔。平均年龄为 41.35 岁。研究发现不同研究环境在获取纳洛酮、给药频率和给药系统方面存在差异。研究结果表明，在预防用药过量和减少伤害干预方面需要更多的教育和培训。对输送系统的研究需要解决芬太尼相关过量用药的增加问题。 NP 可以帮助在当地社区定向分配纳洛酮，促进与减少危害服务机构的合作，并向非专业人士提供基于证据的教育和培训。
Naloxone is an opioid antagonist that can reverse an opioid overdose. Increased opioid-related mortality rates led to greater distribution of naloxone without a prescription and administration of naloxone by laypersons. This study fills a gap in knowledge of naloxone experiences among active users of opioids living in suburban communities. The purpose of this article is to provide nurse practitioners (NPs) with an in-depth understanding of current naloxone use practices on people who experience overdose events. The specific aims are to compare access to naloxone among diverse suburban towns, to examine administration differences across settings, and to understand perspectives on naloxone experiences from people who are actively using opioids. The data for this analysis were drawn from an ethnographic study in the suburban towns around Atlanta, Georgia; Boston, Massachusetts; and New Haven, Connecticut. Short surveys and in-depth interviews were collected. Inductive methods were used to compare data across settings. The sample of 106 included 48% female, 62% white, 24% African American/Black, 13% more than one race, and 21% Hispanic/Latinx. The mean age was 41.35. Differences between study settings in access to naloxone, administration frequency, and delivery systems were found. Findings suggest more education and training is needed in overdose prevention and harm-reduction intervention. Studies on delivery systems need to address the increase in fentanyl-related overdoses. NPs can help to target distribution of naloxone in local communities, facilitate collaboration with harm reduction services, and provide evidence based education and training to laypersons.