Prevalence and determinants of depression in caregivers of cancer patients: A systematic review and meta-analysis.
Prevalence and determinants of depression in caregivers of cancer patients: A systematic review and meta-analysis.
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DOI：
10.1097/md.0000000000011863
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发表时间：
2018-09
期刊：
影响因子：
1.6
通讯作者：
Tian HM
中科院分区：
文献类型：
--
作者：
Geng HM;Chuang DM;Yang F;Yang Y;Liu WM;Liu LH;Tian HM
本研究的目的是估计癌症患者护理人员中抑郁症的患病率，并确定影响癌症护理人员抑郁和生活质量的因素。通过对多个电子数据库的文献检索，检索到相关的研究论文。进行随机效应荟萃分析以获得抑郁和焦虑患病率的汇总估计；他们各自的得分，以及生活质量得分。在个别研究中发现了抑郁症和与抑郁相关的因素与生活质量之间的显著关系。纳入了30项研究。总体而言，这些研究评估了21,149名护理人员（年龄52.65岁[95% CI: 49.65, 55.65]；男性31.14%[28.40,33.89]）。抑郁和焦虑的患病率分别为42.30%[33.31,51.29]%和46.55%[35.59,57.52]%。用护理者生活质量-癌症量表测量的生活质量得分为64.55[47.44,81.66]。患者状况，照顾负担，照顾持续时间，配偶照顾者，照顾者失业，照顾者患有慢性疾病，照顾者睡眠质量，照顾者回避，经济问题，女性性别与抑郁呈正相关而照顾者的整体生活质量，丧前悲伤，照顾者的教育水平，照顾者的年龄，照顾者的连贯感，看护人对病人的束缚与看护人的抑郁呈负相关。在癌症患者的护理人员中发现了相当高的抑郁症患病率。几个因素可能会影响癌症患者护理者的抑郁及其生活质量。
Supplemental Digital Content is available in the text Aim of this study was to estimate the prevalence rate of depression in cancer patient caregivers and to identify factors affecting depression and quality of life of cancer caregivers. Relevant research articles were retrieved after literature search in several electronic databases. Random effects meta-analyses were performed to obtain pooled estimates of the prevalence rates of depression and anxiety; their respective scores, and quality of life scores. Significant relationships between depression and factors related to depression and quality of life reported in individual studies were identified. Thirty studies were included. Overall, 21,149 caregivers were appraised in these studies (age 52.65 years [95% CI: 49.65, 55.65]; 31.14% [28.40, 33.89] men). The prevalence of depression and anxiety were 42.30% [33.31, 51.29] % and 46.55% [35.59, 57.52], respectively. Quality of life score, as measured with Caregiver Quality of Life—Cancer scale was 64.55 [47.44, 81.66]. Patient's condition, caregiving burden, duration of caregiving, spouse caregiver, caregiver being unemployed, caregiver with chronic disease, caregiver's sleep quality, caregiver's avoidance, financial problems, and female sex were positively associated with depression whereas overall quality of life of caregiver, pre-loss grief, caregiver's education level, caregiver's age, caregiver's sense of coherence, and caregiver's bondage with patient were negatively associated with depression in caregivers. A considerably high prevalence of depression is found in cancer patient caregivers. Several factors may affect depression and their quality of life of cancer patient caregivers.