Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation
Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation
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DOI：
10.7554/elife.44119
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发表时间：
2019-04-03
期刊：
影响因子：
7.7
通讯作者：
Maler, Len
中科院分区：
文献类型：
--
作者：
Fotowat, Haleh;Lee, Candice;Maler, Len
大多数脊椎动物使用主动感知策略来感知、认知和控制运动活动。这些策略包括定向的身体/传感器运动或增加离散的感觉采样事件。弱电鱼类Gymnotus sp.在黑暗中航行时使用其活跃的电子感官。为了增加电感采样，在航行过程中，电器官的放电率会发生瞬变增加。Gymnotus还使用刻板的向后游泳作为一种重要的主动感觉形式，将物体带向电感受器致密的中心凹状头部区域。我们无线记录了自由游泳的裸腹鱼大脑皮层的神经活动。刺激性活动很稀少，仅在游泳时发生。值得注意的是，大多数单位倾向于在向后游泳时开枪，他们的活动平均伴随着感官采样的增加。我们的结果首次描述了硬骨鱼大脑中类似海马区(CA3)的神经活动，并将其与空间环境特征的主动感知联系起来。
Most vertebrates use active sensing strategies for perception, cognition and control of motor activity. These strategies include directed body/sensor movements or increases in discrete sensory sampling events. The weakly electric fish, Gymnotus sp., uses its active electric sense during navigation in the dark. Electric organ discharge rate undergoes transient increases during navigation to increase electrosensory sampling. Gymnotus also use stereotyped backward swimming as an important form of active sensing that brings objects toward the electroreceptor dense fovea-like head region. We wirelessly recorded neural activity from the pallium of freely swimming Gymnotus. Spiking activity was sparse and occurred only during swimming. Notably, most units tended to fire during backward swims and their activity was on average coupled to increases in sensory sampling. Our results provide the first characterization of neural activity in a hippocampal (CA3)-like region of a teleost fish brain and connects it to active sensing of spatial environmental features.