Personalised Adherence Support for Maintenance Treatment of Inflammatory Bowel Disease: A Tailored Digital Intervention to Change Adherence-related Beliefs and Barriers
Personalised Adherence Support for Maintenance Treatment of Inflammatory Bowel Disease: A Tailored Digital Intervention to Change Adherence-related Beliefs and Barriers
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DOI：
10.1093/ecco-jcc/jjz034
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发表时间：
2020-10-01
影响因子：
8
通讯作者：
Horne, Rob
中科院分区：
文献类型：
--
作者：
Chapman, Sarah;Sibelli, Alice;Horne, Rob
背景和目标：改善药物依从性的干预措施可能更有效，如果量身定制，解决与治疗相关的信念，克服日常使用的实际障碍。我们评估了是否有一种算法，定制支持，以解决知觉和实际的障碍，坚持，减少障碍，并接受炎症性肠病患者[IBD].Methods：参与者IBD，规定硫唑嘌呤和/或美沙拉秦，通过患者组，社会媒体和医院诊所招募，并分配到干预组或对照组。在线干预包括针对IBD和维持治疗的信念而定制的信息，并提供关于克服定期服药的实际困难的建议。内容是个性化的，以解决特定的感知和实际的障碍，确定了一个预先筛选工具。经验证的问卷调查评估的障碍，在基线和1和3个月的follow-up.Results：共329名参与者被分配到干预En = 153]和控制在= 176]组的依从性和相关的次要outcomes;不到一半[46.2%]完成后续行动。在1个月和3个月时，干预组对IBD药物治疗的担忧明显减少[p
Background and Aims: Interventions to improve adherence to medication may be more effective if tailored to the individual, addressing adherence-related beliefs about treatment and overcoming practical barriers to daily use. We evaluated whether an algorithm, tailoring support to address perceptual and practical barriers to adherence, reduced barriers and was acceptable to patients with inflammatory bowel disease [IBD].Methods: Participants with IBD, prescribed azathioprine and/or mesalazine, were recruited via patient groups, social media, and hospital clinics and allocated to Intervention or Control Groups. The online intervention comprised messages tailored to address beliefs about IBD and maintenance treatment and to provide advice on overcoming practical difficulties with taking regular medication. The content was personalised to address specific perceptual and practical barriers identified by a pre-screening tool. Validated questionnaires assessed barriers to adherence and related secondary outcomes at baseline and at 1 and 3 months of follow-up.Results: A total of 329 participants were allocated to the Intervention En = 153] and Control In= 176] Groups; just under half [46.2%] completed follow-up. At 1 and 3 months, the Intervention Group had significantly fewer concerns about IBD medication [p