Long-term selection for a quantitative character in large replicate populations of Drosophila melanogaster : II. Lethals and visible mutants with large effects
Long-term selection for a quantitative character in large replicate populations of Drosophila melanogaster : II. Lethals and visible mutants with large effects
复制标题
果蝇大量复制群体中数量性状的长期选择：II。
DOI：
10.1017/s0016672300013902
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发表时间：
1980
影响因子：
1.5
通讯作者：
B. Yoo
中科院分区：
文献类型：
--
作者：
B. Yoo
第二和第三染色体上的致死频率估计三次在6个重复线的果蝇选择增加腹部刚毛数量，在G 14-16，G 37-44和G 79。在G 14-16以约5%或更高的频率检测到10起致死事件，其中只有一起在随后的测试中复发。在G37 -44发现了另外10个以前未发现的致死性，在G79发现了5个最常见的致死性。在上次测试中，检测到了15种可能的新致命病例，其中至少4种似乎已经确定。此外，还发现了6个回复突变（从sc到sc+），一个新的突变体在scute位点和sea。某些致死突变体和可见突变体对所选性状的影响很大，而且变化很大，但并不总是足以解释观察到的频率。首次在G37 -44和G79检测到的主要致死性很可能是在选择过程中发生的“突变”（广义上）。这种“突变”的可能起源进行了讨论，建议已知的隐性致死突变率不会与观察到的“突变”发生频率不相容。
Lethal frequencies on the second and third chromosomes were estimated three times in six replicate lines of Drosophila melanogaster selected for increased abdominal bristle number, at G 14-16, G 37-44 and G 79. Ten lethals were detected at a frequency of about 5 % or higher at G 14-16, of which only one recurred in subsequent tests. Another ten lethals which had not been detected previously were found at G 37-44, and the 5 most frequent ones recurred at G 79. In the last test, 15 presumably new lethals were detected, of which at least 4 appeared well established. In addition, six reversions (from sc to sc+), a new mutant at the scute locus and sea were discovered. The effects on the selected character of some lethals and visible mutants were large and variable, but not always sufficient to explain the observed frequencies. The major lethals detected at G 37-44 and G 79 for the first time were most probably 'mutations' (in the broad sense) which occurred during selection. The likely origins of such ' mutations' were discussed, with a suggestion that the known mutation rate for recessive lethals would not be incompatible with the observed frequency of occurrence of the 'mutations'.