PERIPHERAL CONTROL OF THE CATS STEP CYCLE .2. ENTRAINMENT OF THE CENTRAL PATTERN GENERATORS FOR LOCOMOTION BY SINUSOIDAL HIP MOVEMENTS DURING FICTIVE LOCOMOTION
PERIPHERAL CONTROL OF THE CATS STEP CYCLE .2. ENTRAINMENT OF THE CENTRAL PATTERN GENERATORS FOR LOCOMOTION BY SINUSOIDAL HIP MOVEMENTS DURING FICTIVE LOCOMOTION
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DOI：
10.1111/j.1748-1716.1983.tb07267.x
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发表时间：
1983-01-01
期刊：
影响因子：
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通讯作者：
GRILLNER, S
中科院分区：
文献类型：
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作者：
ANDERSSON, O;GRILLNER, S
静脉注射去甲肾上腺素能激动剂的急性低位脊髓和curarized猫可以引起传出爆发模式，其可以记录在肌肉神经丝中，并且可以被称为“虚构运动”。反馈，在髋关节的运动所产生的效果，可以施加在中央网络产生“虚构的运动”进行了研究。中央网络通过curarization从产生任何主动运动中解耦。运动模式可以通过应用正弦髋关节运动来实现，即使在进行了非常广泛的腿部去神经支配后，仅留下髋关节周围的一些肌肉和髋关节受神经支配。在屈曲运动，传出到不同的屈肌肌肉变得活跃，并在相反方向（伸展）的运动过程中，传出到伸肌活跃。随着运动频率的增加，屈肌和伸肌爆发的起始时间在运动周期中延迟。伸肌爆发的持续时间随运动周期的变化而变化，而纯屈肌的爆发持续时间变化较小。传出爆发活动的频率范围内夹带在一个严格的1：1的关系，运动变化之间的5-70%以上和以下的休息爆发期。在具有窄的1：1范围的制备中，在该范围之外遇到相对协调。在这些情况下，屈肌爆发持续时间取决于髋关节运动周期中爆发出现的位置。
Acute low spinal and curarized cats injected with noradrenergic agonists i.v. can elicit an efferent burst pattern which can be recorded in muscle nerve filaments and can be referred to as "fictive locomotion". The effect that feedback, arising from movements in the hip joint, can exert on the central network generating "fictive locomotion" was investigated. The central network is uncoupled from generating any active movements by curarization. The motor pattern could be entrained by applying sinusoidal hip movements, even when a very extensive denervation of the leg had been performed leaving only some of the muscles around the hip and the hip joint innervated. During flexion movements, efferents to different flexor muscles became active and during movements in the reverse direction (extension), efferents to extensors were active. With an increasing movement frequency the onsets of both flexor and extensor bursts were delayed in the movement cycle. The duration of the extensor bursts varied markedly with the movement cycle, whereas pure flexors changes less in burst duration. The frequency range within which the efferent burst activity was entrained in a strict 1:1 relation to the movement varied between 5-70% above and below the resting burst period. In preparations with a narrow 1:1 range, a relative coordination was encountered outside this range. The flexor burst duration was in these cases dependent on where in the hip movement cycle the bursts appeared.