Correlation between radiation dose and histopathological findings in patients with gliblastoma treated with boron neutron capture therapy (BNCT)
Correlation between radiation dose and histopathological findings in patients with gliblastoma treated with boron neutron capture therapy (BNCT)
复制标题
DOI：
10.1016/j.apradiso.2013.12.014
复制
发表时间：
2014-06-01
影响因子：
1.6
通讯作者：
Kumada, H.
中科院分区：
文献类型：
--
作者：
Kageji, T.;Mizobuchi, Y.;Kumada, H.
本研究的目的是阐明接受硼中子俘获治疗（BNCT）的多形性胶质母细胞瘤（GBM）患者的放射剂量与组织病理学结果之间的关系。对8例患者的标本进行了组织病理学检查，其中3例进行了抢救手术，5例进行了尸检。对于原发部位GBM的组织病理学治疗，总肿瘤体积（GTV）和临床靶体积（CTV）的最佳最小剂量分别为68 Gy(w)和44 Gy(w)。(C) 2014年Elsevier Ltd.出版
The purpose of this study was to clarify the correlation between the radiation dose and histopathological findings in patients with glioblastoma multiforme (GBM) treated with boron neutron capture therapy (BNCT). Histopathological studies were performed on specimens from 8 patients, 3 had undergone salvage surgery and 5 were autopsied. For histopathological cure of GBM at the primary site, the optimal minimal dose to the gross tumor volume (GTV) and the clinical target volume (CTV) were 68 Gy(w) and 44 Gy(w), respectively. (C) 2014 Published by Elsevier Ltd.