REVERSIBLE PRESSURE-TEMPERATURE DENATURATION OF CHYMOTRYPSINOGEN

REVERSIBLE PRESSURE-TEMPERATURE DENATURATION OF CHYMOTRYPSINOGEN
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DOI:
10.1021/bi00789a002
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发表时间:
1971-01-01
期刊:
影响因子:
2.9
通讯作者:
HAWLEY, SA
HAWLEY, SA
中科院分区:
生物学3区
文献类型:
--
作者:
HAWLEY, SA

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S. A. Hawley abstract: The pressure-temperature-reversibletransition surface for chymotrypsinogen at pH 2.07 has been determined by ultraviolet difference spectra over the temperatureinterval 8.5 to 700 between atmospheric pressure and 7000 atm. Assum-ing the transition involves two states, it is shown that the sur-face can be fit to a relatively simple equation of state which elicits approximately elliptical contours of constant freeenergy difference on the pressure-temperature plane. Similar