Sleep quality and daytime sleepiness are not associated with cognition in heart failure.

Sleep quality and daytime sleepiness are not associated with cognition in heart failure.
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睡眠质量和白天嗜睡与心力衰竭的认知无关。

DOI:
10.1016/j.jpsychores.2018.08.003
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发表时间:
2018
影响因子:
4.7
通讯作者:
Hughes,JoelW
Hughes,JoelW
中科院分区:
医学3区
文献类型:
--
作者:
Walter,FawnA;Ede,David;Hawkins,MistyAW;Dolansky,MaryA;Gunstad,John;Josephson,Richard;Moore,ShirleyM;Hughes,JoelW

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背景心力衰竭患者在睡眠和认知能力方面表现出共同的损害。睡眠质量与心力衰竭患者的认知能力受损有关,但报道并不一致。在这项研究中,我们考察了高频患者的睡眠质量、日间嗜睡和认知功能之间的关系。方法和结果从门诊招募的267名心力衰竭患者(年龄 = 69.1 ± 9.3),主要是高加索人(74.9%),男性(59.6%)稳定的心力衰竭患者。这项横断面研究是对前瞻性观察性研究的二次分析。评估的认知功能领域包括:整体认知功能、注意力、记忆和执行功能。分别使用匹兹堡睡眠质量指数(PSQI)和爱普沃斯嗜睡量表(ESS)评估睡眠质量和日间困倦。在控制了性别、纽约心脏协会(NYHA)级别、教育程度、抑郁症状和医疗合并症后,分别进行了多个层次的线性回归,以确定认知功能和睡眠质量与日间嗜睡之间的关系。经α充气校正后,认知功能与睡眠质量或日间嗜睡无关。结论心力衰竭患者的认知功能与睡眠质量或日间嗜睡无关,其他因素可能对认知表现有较大影响。
BackgroundIndividuals with heart failure (HF) exhibit comorbid impairments in both sleep and cognitive performance. Sleep quality has been associated with impaired cognitive performance in HF patients, but reports are inconsistent. In this study, we examined associations between sleep quality, daytime sleepiness, and cognitive function in HF.Methods and resultsParticipants were 267 (age = 69.1 ± 9.3) mostly Caucasian (74.9%), male (59.6%) stable HF patients recruited from outpatient settings. This cross-sectional study was a secondary analysis of a prospective observational study. Cognitive function domains assessed included: global cognitive function, attention, memory, and executive function. Sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS), respectively. Separate multiple hierarchical linear regressions were conducted to determine associations between cognitive function and sleep quality and daytime sleepiness, after controlling for sex, New York Heart Association (NYHA) class, education, depressive symptoms, and medical comorbidities. Cognitive function was not associated with sleep quality or daytime sleepiness after alpha inflation corrections were applied.ConclusionsCognitive function in HF is not associated with sleep quality or daytime sleepiness; other factors may exert greater influence on cognitive performance.
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对低 pH 值的适应改变了哺乳动物细胞的热和热化学反应。
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