Genital herpes - Type-specific antibodies for diagnosis and management

Genital herpes - Type-specific antibodies for diagnosis and management
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DOI:
10.1016/s0733-8635(05)70048-6
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发表时间:
1998-10-01
影响因子:
2.4
通讯作者:
Ashley, RL
Ashley, RL
中科院分区:
医学2区
文献类型:
--
作者:
Ashley, RL

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生殖器HSV-2感染的患病率在过去二十年中增加了30%以上,目前每5名成年人中就有1名HSV-2抗体阳性。15%的白色男性、20%的白色女性、35%的黑人男性和55%的黑人女性为HSV-2血清阳性。HSV-2的流行率在青少年中增加了5倍,在20多岁的人中增加了一倍。(10)由于HSV-1导致20%至40%的生殖器疱疹首次发作,这些数字低估了该国生殖器疱疹的总负担。
Genital HSV-2 infections have increased in prevalence by more than 30% over the last two decades with 1 in 5 adults now positive for antibodies to HSV-2. Fifteen percent of white men, 20% of white women, 35% of black men, and 55% of black women are HSV-2 seropositive. Prevalence of HSV-2 has in creased 5-fold among teenagers and has doubled among those in their twenties.(10) Since HSV-1 causes from 20% to 40% of first episodes of genital herpes, these figures underestimate the total burden of genital herpes in this country.